Plasma pharmacokinetics, pulmonary disposition, and safety of subcutaneous gamithromycin in alpacas.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.13045
Abstract: The study objective was to determine the disposition of gamithromycin in plasma, peripheral blood polymorphonuclear cells (PMNs), pulmonary epithelial lining fluid (PELF), and bronchoalveolar lavage (BAL) cells in alpacas. A single subcutaneous injection of gamithromycin… read more here.
Keywords: bal cells; disposition; plasma; gamithromycin alpacas ... See more keywords
Pharmacodynamic Target Assessment and PK/PD Cutoff Determination for Gamithromycin Against Streptococcus suis in Piglets
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.945632
Abstract: Gamithromycin is a long-acting azalide antibiotic that has been developed recently for the treatment of swine respiratory diseases. In this study, the pharmacokinetic/pharmacodynamic (PK/PD) targets, PK/PD cutoff, and optimum dosing regimen of gamithromycin were evaluated… read more here.
Keywords: assessment; streptococcus suis; pharmacodynamic target; gamithromycin ... See more keywords