Articles with "gamma chain" as a keyword



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Corrigendum: Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis

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Published in 2017 at "Nature Communications"

DOI: 10.1038/ncomms15185

Abstract: Nature Communications 8: Article number: 13708 (2016); Published: 16 Dec 2016; Updated: 4 Apr 2017 The financial support for this Article was not fully acknowledged. The acknowledgements should have included the following: The European Community… read more here.

Keywords: interleukin bypasses; chain signalling; bypasses common; gamma chain ... See more keywords
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Molecular dynamics-based analyses of the structural instability and secondary structure of the fibrinogen gamma chain protein with the D356V mutation

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Published in 2017 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2016.1229634

Abstract: Mutations in the fibrinogen gamma chain (FGG) gene have been associated with various disorders, such as dysfibrinogenemia, thrombophilia, and hypofibrinogenemia. A literature survey showed that a residue exchange in fibrinogen Milano I from γ Asp… read more here.

Keywords: protein; fibrinogen gamma; secondary structure; gamma chain ... See more keywords
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Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse.

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Published in 2018 at "Wellcome open research"

DOI: 10.12688/wellcomeopenres.14493.1

Abstract: Background: Mutations of the common cytokine receptor gamma chain (γc) cause Severe Combined Immunodeficiency characterized by absent T and NK cell development. Although stem cell therapy restores these lineages, residual immune defects are observed that… read more here.

Keywords: trans presentation; cell; gamma chain; dendritic cell ... See more keywords
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Case Report: Interleukin-2 Receptor Common Gamma Chain Defect Presented as a Hyper-IgE Syndrome

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.696350

Abstract: X-linked severe combined immunodeficiency (X-SCID) is caused by mutations of IL2RG, the gene encoding the interleukin common gamma chain (IL-2Rγ or γc) of cytokine receptors for interleukin (IL)-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Hypomorphic… read more here.

Keywords: receptor; gamma chain; common gamma; case report ... See more keywords
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Increased Immunoglobulin Gamma-3 Chain C in the Serum, Saliva, and Urine of Patients with Systemic Lupus Erythematosus

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24086927

Abstract: Immunoglobulin gamma-3 chain C (IGHG3) levels have been detected in the blood and tissue of patients with systemic lupus erythematosus (SLE). This study aims to assess its clinical value by measuring and comparing levels of… read more here.

Keywords: immunoglobulin gamma; gamma chain; serum; patients systemic ... See more keywords
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Advancements of Common Gamma-Chain Family Cytokines in Cancer Immunotherapy

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Published in 2022 at "Immune Network"

DOI: 10.4110/in.2022.22.e5

Abstract: The approval of immunotherapies such as checkpoint inhibitors (CPIs), adoptive cell therapies and cancer vaccines has revolutionized the way cancer treatment is approached. While immunotherapies have improved clinical outcome in a variety of tumor types,… read more here.

Keywords: gamma chain; common gamma; advancements common; cancer ... See more keywords