Gabapentin attenuates intestinal inflammation: Role of PPAR-gamma receptor.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.172974
Abstract: Gabapentin is an anticonvulsant drug that is also used for post-herpetic neuralgia and neuropathic pain. Recently, gabapentin showed anti-inflammatory effect. Nuclear factor kappa B (NFκB) is a regulator of the inflammatory process, and Peroxisome Proliferator-activated… read more here.
Keywords: gamma receptor; gamma; gabapentin; ppar gamma ... See more keywords
The Fab portion of immunoglobulin G has sites in the CL domain that interact with Fc gamma receptor IIIa
Sign Up to like & getrecommendations! Published in 2022 at "mAbs"
DOI: 10.1080/19420862.2022.2038531
Abstract: ABSTRACT The interaction between IgG and Fc gamma receptor IIIa (FcγRIIIa) is essential for mediating immune responses. Recent studies have shown that the antigen binding fragment (Fab) and Fc are involved in IgG-FcγRIII interactions. Here,… read more here.
Keywords: interaction; igg riii; riii; gamma receptor ... See more keywords
A case of recurrent herpes simplex 2 encephalitis, VZV reactivations, and dominant partial interferon-gamma-receptor-1 deficiency supports relevance of IFNgamma for antiviral defense in humans
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Pediatrics"
DOI: 10.1186/s40348-020-00106-4
Abstract: Background Unlike infections with mycobacteria, reports of unusual viral infections in interferon-gamma-receptor (IFNγR) deficient patients are scarce. Therefore, discussion about increased susceptibility to viral infections in these patients is ongoing. Case presentation We describe a… read more here.
Keywords: gamma receptor; dominant partial; case; interferon gamma ... See more keywords
There Is (Scientific) Strength in Numbers: A Comprehensive Quantitation of Fc Gamma Receptor Numbers on Human and Murine Peripheral Blood Leukocytes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00118
Abstract: Antibodies are essential mediators of immunological defense mechanisms, are clinically used as therapeutic agents, but are also functionally involved in various immune-mediated disorders. Whereas IgG antibodies accomplish some of their biological tasks autonomously, many functions… read more here.
Keywords: quantitation gamma; gamma receptor; comprehensive quantitation; scientific strength ... See more keywords
Functional Fc Gamma Receptor Gene Polymorphisms and Long-Term Kidney Allograft Survival
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DOI: 10.3389/fimmu.2021.724331
Abstract: The functional Fc gamma receptor (FcγR) IIIA polymorphism FCGR3A-V/F158 was earlier suggested to determine the potential of donor-specific HLA antibodies to trigger microcirculation inflammation, a key lesion of antibody-mediated renal allograft rejection. Associations with long-term… read more here.
Keywords: functional gamma; allograft survival; gamma receptor; long term ... See more keywords
The Low Expression of Fc-Gamma Receptor III (CD16) and High Expression of Fc-Gamma Receptor I (CD64) on Neutrophil Granulocytes Mark Severe COVID-19 Pneumonia
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12082010
Abstract: Hyperinflammation through neutrophil granulocytes contributes to disease severity in COVID-19 pneumonia and promotes acute lung failure. Understanding the mechanisms of the dysregulations within the myeloid cell compartment may help to improve therapies for severe COVID-19… read more here.
Keywords: gamma receptor; receptor; expression gamma; neutrophil granulocytes ... See more keywords