Comparative evaluation of involved free light chain and monoclonal spike as markers for progression from monoclonal gammopathy of undetermined significance to multiple myeloma
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Hematology"
DOI: 10.1002/ajh.25999
Abstract: Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant clonal plasma cell disorder, with a 1% yearly risk of progression to multiple myeloma (MM). Evolution of M‐spike and serum free light chain (sFLC) during follow‐up… read more here.
Keywords: monoclonal gammopathy; risk; spike; progression ... See more keywords
Multi‐trajectory models of serum biomarkers among patients with monoclonal gammopathy of undetermined significance
Sign Up to like & getrecommendations! Published in 2022 at "Hematological Oncology"
DOI: 10.1002/hon.2992
Abstract: Understanding the progression of monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) is needed to identify patients who would benefit from closer clinical surveillance. Given that two of the defining criteria of MM… read more here.
Keywords: gammopathy undetermined; undetermined significance; group; multi trajectory ... See more keywords
Diagnostic relevance of 2-[18 F]-FDG PET/CT in patients recently diagnosed with monoclonal gammopathy of undetermined significance.
Sign Up to like & getrecommendations! Published in 2022 at "Hematological oncology"
DOI: 10.1002/hon.3085
Abstract: 2-[18 F]-FDG PET/CT is a useful diagnostic technique to assess bone and soft tissue disease in multiple myeloma but is not recommended by the International Myeloma Working Group for the evaluation of monoclonal gammopathy of… read more here.
Keywords: fdg; gammopathy undetermined; undetermined significance; monoclonal gammopathy ... See more keywords
Contributions of the Bone Microenvironment to Monoclonal Gammopathy of Undetermined Significance Pathogenesis
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DOI: 10.1007/s11914-018-0479-z
Abstract: Purpose of ReviewMGUS (monoclonal gammopathy of undetermined significance) is a plasma cell disorder characterized by a moderate increase in serum monoclonal protein (≤ 3 g/dL), an increase in bone marrow plasma cell infiltration (≤ 10%) and the absence… read more here.
Keywords: monoclonal gammopathy; undetermined significance; gammopathy undetermined; bone microenvironment ... See more keywords
Prothrombotic abnormalities in patients with multiple myeloma and monoclonal gammopathy of undetermined significance.
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DOI: 10.1016/j.thromres.2021.03.015
Abstract: BACKGROUND Multiple myeloma (MM) and its precursor condition, monoclonal gammopathy of undetermined significance (MGUS) have an increased risk of thrombotic events, especially during anti-myeloma treatment. Many different underlying causes for this hypercoagulability have been suggested,… read more here.
Keywords: monoclonal gammopathy; abnormalities patients; multiple myeloma; undetermined significance ... See more keywords
Prognostic significance of interphase FISH in monoclonal gammopathy of undetermined significance
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DOI: 10.1038/s41375-018-0030-3
Abstract: Monoclonal gammopathy of undetermined significance (MGUS) is a clonal plasma cell (PC) disorder characterized by the presence in serum of monoclonal protein read more here.
Keywords: monoclonal gammopathy; patients mgus; fish testing; undetermined significance ... See more keywords
Body mass index associated with monoclonal gammopathy of undetermined significance (MGUS) progression in Olmsted County, Minnesota.
Sign Up to like & getrecommendations! Published in 2022 at "Blood cancer journal"
DOI: 10.1038/s41408-022-00659-9
Abstract: Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant clonal disorder that progresses to multiple myeloma (MM), or other plasma-cell or lymphoid disorders at a rate of 1%/year. We evaluate the contribution of body mass… read more here.
Keywords: gammopathy undetermined; progression; mgus progression; bmi ... See more keywords
Monoclonal Gammopathy of Undetermined Significance After Kidney Transplantation: Single-Center Experience
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DOI: 10.1097/tp.0000000000001884
Abstract: Background Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic premalignant plasma cell disorder. Prevalence and clinical outcomes of MGUS in kidney transplant (KT) recipients have been previously reported in few studies with conflicting results.… read more here.
Keywords: monoclonal gammopathy; undetermined significance; gammopathy undetermined; mgus ... See more keywords
Abstract 5925: Prevalence of clonal hematopoiesis in patients with monoclonal gammopathy of undetermined significance
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DOI: 10.1158/1538-7445.am2023-5925
Abstract: INTRODUCTION: Clonal hematopoiesis of indeterminate potential (CHIP) is defined by the expansion of progeny derived from hematopoietic stem cells that have acquired somatic mutations at a VAF greater than 2%. CHIP manifests in 10% of… read more here.
Keywords: gammopathy undetermined; undetermined significance; risk; monoclonal gammopathy ... See more keywords
Coexistence of Prefibrotic Myelofibrosis with Monoclonal Gammopathy of Undetermined Significance: A Case Report
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DOI: 10.1159/000516746
Abstract: The coexistence of dual hematological neoplasms is an unusual and challenging presentation due to the different combination of etiopathology. The presentation of synchronous dual hematological malignancies can be one of the 3 types: myeloid +… read more here.
Keywords: monoclonal gammopathy; myelofibrosis; case; coexistence ... See more keywords
Risk factors for severe infection and mortality in COVID-19 and monoclonal gammopathy of undetermined significance
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DOI: 10.1182/blood.2022017616
Abstract: Two Letters to Blood address the risks of COVID-19 in populations with precursors of hematological disease. In the first article, Miller and colleagues report on whether clonal hematopoiesis of intermediate potential (CHIP) is associated with… read more here.
Keywords: gammopathy undetermined; undetermined significance; mortality; severe infection ... See more keywords