Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet‐induced obese and biopsy‐confirmed mouse model of NASH
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DOI: 10.1111/cts.13235
Abstract: Non‐alcoholic steatohepatitis (NASH) has emerged as a major challenge for public health because of high global prevalence and lack of evidence‐based therapies. Most animal models of NASH lack sufficient validation regarding disease progression and pharmacological… read more here.
Keywords: dietary intervention; nash; gan diet; gan dio ... See more keywords
2020-P: Comparable Disease Progression in GAN and AMLN Diet-Induced Obese Mouse Models of Biopsy-Confirmed Nonalcoholic Steatohepatitis
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DOI: 10.2337/db19-2020-p
Abstract: Amylin Liver NASH (AMLN) diet-induced obese C57Bl/6J (DIO-NASH) and ob/ob (ob/ob-NASH) mouse models display clinical translatability with respect to metabolic and histopathological changes associated with nonalcoholic steatohepatitis (NASH). A recent FDA ban on trans-fats in… read more here.
Keywords: mice; amln diet; nash mice; gan diet ... See more keywords