In vivo efficacy of ganciclovir by using single-walled carbon nanotubes as a drug carrier against infectious spleen and kidney necrosis virus in mandarin fish
Sign Up to like & getrecommendations! Published in 2020 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2020.735434
Abstract: Abstract Infectious spleen and kidney necrosis virus (ISKNV) cause a high mortality disease which leads to a significant economic loss on mandarin fish in China. At present, there is no effective drug against this fatal… read more here.
Keywords: mandarin fish; infection; group; infectious spleen ... See more keywords
Improved Protease-Targeting and Biopharmaceutical Properties of Novel Prodrugs of Ganciclovir.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00792
Abstract: The prodrug strategy has been frequently employed as a chemical approach for overcoming the disadvantages of existing parent drugs. In this report, we synthesized four monoester prodrugs of ganciclovir, an anticytomegalovirus drug, and demonstrated their… read more here.
Keywords: ganciclovir prodrugs; hcmv protease; prodrugs ganciclovir; biopharmaceutical properties ... See more keywords
Treatment of cytomegalovirus anterior segment infection with intravitreal injection of ganciclovir in adjunction with or without oral valganciclovir: a long-term results
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82637-y
Abstract: We evaluated the therapeutic outcome of intravitreal injection (IVI) of ganciclovir with/without oral valganciclovir for cytomegalovirus (CMV) anterior segment infection. We enrolled 61 patients (61 eyes) with PCR-proven CMV anterior segment infection. IVI of ganciclovir… read more here.
Keywords: infection; anterior segment; segment infection; ganciclovir ... See more keywords
565: ANALYSIS OF FUNGITELL ASSAY AND IVIG INTERACTIONS IN ALLOGENIC BONE MARROW TRANSPLANT PATIENTS
Sign Up to like & getrecommendations! Published in 2019 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000551317.14805.15
Abstract: Learning Objectives: The clinical utility of ganciclovir therapeutic drug monitoring (TDM) is unknown. Methods: We conducted a single center, retrospective analysis of adult patients with active viral infection treated with valganciclovir or intravenous ganciclovir with… read more here.
Keywords: serum ganciclovir; symptomatology; ganciclovir tdm; analysis ... See more keywords
Clinical features, diagnosis and treatment outcomes of cytomegalovirus endotheliitis in Hong Kong
Sign Up to like & getrecommendations! Published in 2018 at "Acta Ophthalmologica"
DOI: 10.1111/aos.13109
Abstract: Editor, C orneal endotheliitis refers to the specific inflammation of corneal endothelium (Khodadoust & Attarzadeh 1982). The clinical features include corneal oedema, keratic precipitates, trace to moderate anterior chamber reaction and destruction of corneal endothelium… read more here.
Keywords: diagnosis; cmv endotheliitis; treatment; endotheliitis ... See more keywords
Ganciclovir‐resistant post‐transplant cytomegalovirus infection due to combined deletion mutation at codons 595‐596 of the UL97 gene
Sign Up to like & getrecommendations! Published in 2019 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13168
Abstract: The development of antiviral‐resistant cytomegalovirus (CMV) infection complicates the management of transplant recipients. We describe the case of a 65‐year‐old male who developed CMV disease on valganciclovir prophylaxis (donor CMV IgG positive, recipient CMV IgG… read more here.
Keywords: cmv; ul97 gene; transplant; ganciclovir ... See more keywords
Evaluation of compounded cidofovir, famciclovir, and ganciclovir for the treatment of feline herpesvirus ocular surface disease in shelter-housed cats.
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary ophthalmology"
DOI: 10.1111/vop.13031
Abstract: OBJECTIVE To assess the efficacy of compounded cidofovir, famciclovir, and ganciclovir for the treatment of feline herpesvirus type 1 (FHV-1) ocular surface disease. ANIMALS STUDIED 132 shelter-housed cats qPCR positive for FHV-1. PROCEDURES A masked… read more here.
Keywords: compounded cidofovir; day; cidofovir; placebo ... See more keywords
Resistance to a Nucleoside Analog Antiviral Drug from More Rapid Extension of Drug-Containing Primers
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DOI: 10.1128/mbio.03492-20
Abstract: While resistance to antiviral drugs can hinder their clinical use, understanding resistance mechanisms can illuminate how these drugs and their targets act. We studied a substitution in the human cytomegalovirus (HCMV) DNA polymerase that confers… read more here.
Keywords: dna; drug; resistance; polymerase ... See more keywords
Efficacy and safety of an extemporaneous preparation of 2% ganciclovir eye drops in CMV anterior uveitis
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Open Ophthalmology"
DOI: 10.1136/bmjophth-2016-000061
Abstract: Background To evaluate the efficacy and safety of an extemporaneous preparation of 2% ganciclovir topical eye drops in cytomegalovirus (CMV) anterior uveitis because many studies have confirmed the benefits of topical ganciclovir in varying concentrations.… read more here.
Keywords: cmv anterior; anterior uveitis; extemporaneous preparation; eye drops ... See more keywords
Efficacy of ganciclovir versus foscarnet in ganciclovir-resistant cytomegalovirus retinitis: A case report.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of ophthalmology"
DOI: 10.1177/11206721221136316
Abstract: PURPOSE To report a case of cytomegalovirus (CMV) retinitis improved by treatment with ganciclovir in a patient with ganciclovir-resistant CMV infection associated with Good syndrome. STUDY DESIGN Case report. RESULT A 52-year-old gentleman with Good… read more here.
Keywords: retinitis; report; case; ganciclovir ... See more keywords
Efficacy of Artesunate for Treatment of Cytomegalovirus Reactivations in Allogeneic Haematopoietic Stem Cell Transplant Recipients Who Are Intolerant/Unsuitable for Ganciclovir Therapy
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-128766
Abstract: Background: Cytomegalovirus (CMV) reactivations are common post allogeneic stem cell transplant (ASCT) especially in developing countries like India, where most of the patients as well as donors are CMV seropositive. Ganciclovir is the drug of… read more here.
Keywords: cmv; line; stem cell; artesunate ... See more keywords