Developmental Changes in Potassium Channels in Low Threshold Myelinated Ah-type Vagal Ganglion Neurons in Rats
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2020.01.004
Abstract: Myelinated Ah-type vagal ganglion neurons (VGNs) were specific subpopulation in adult females, rather than neonate and key players in sexual dimorphism in baroreflex afferent function and closely associated with estrogen. However, the gender related development… read more here.
Keywords: vagal ganglion; ganglion neurons; myelinated type; type vagal ... See more keywords
Tuning Surface and Topographical Features to Investigate Competitive Guidance of Spiral Ganglion Neurons.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b09258
Abstract: Cochlear Implants (CIs) suffer from limited tonal resolution due, in large part, to spatial separation between stimulating electrode arrays and primary neural receptors. In this work, a combination of physical and chemical micropatterns, formed on… read more here.
Keywords: ganglion neurons; tuning surface; surface topographical; spiral ganglion ... See more keywords
3D Ti3C2Tx MXene–Matrigel with Electroacoustic Stimulation to Promote the Growth of Spiral Ganglion Neurons
Sign Up to like & getrecommendations! Published in 2022 at "ACS Nano"
DOI: 10.1021/acsnano.2c06306
Abstract: Cochlear implantation has become the most effective treatment method for patients with profound and total hearing loss. However, its therapeutic efficacy is dependent on the number and normal physiological function of cochlear implant-targeted spiral ganglion… read more here.
Keywords: cochlear implant; ganglion neurons; mxene matrigel; ti3c2tx mxene ... See more keywords
Sevoflurane modulation of tetrodotoxin-resistant Na+ channels in small-sized dorsal root ganglion neurons of rats
Sign Up to like & getrecommendations! Published in 2021 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001731
Abstract: Objective Volatile anesthetics are widely used for general anesthesia during surgical operations. Voltage-gated Na+ channels expressed in central neurons are major targets for volatile anesthetics; but it is unclear whether these drugs modulate native tetrodotoxin-resistant… read more here.
Keywords: ganglion neurons; voltage; root ganglion; tetrodotoxin resistant ... See more keywords
Effect of Tissue Heterogeneity on the Transmembrane Potential of Type-1 Spiral Ganglion Neurons: A Simulation Study
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2017.2700361
Abstract: Electric stimulation of the auditory nerve by cochlear implants has been a successful clinical intervention to treat the sensory neural deafness. In this pathological condition of the cochlea, type-1 spiral ganglion neurons in Rosenthal's canal… read more here.
Keywords: ganglion neurons; tissue heterogeneity; rosenthal canal; spiral ganglion ... See more keywords
KCNQ2/3/5 channels in dorsal root ganglion neurons can be therapeutic targets of neuropathic pain in diabetic rats
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Pain"
DOI: 10.1177/1744806918793229
Abstract: Background Diabetic neuropathic pain is poorly controlled by analgesics, and the precise molecular mechanisms underlying hyperalgesia remain unclear. The KCNQ2/3/5 channels expressed in dorsal root ganglion neurons are important in pain transmission. The expression and… read more here.
Keywords: ganglion neurons; root ganglion; kcnq2 channels; dorsal root ... See more keywords
Adrenergic receptors inhibit TRPV1 activity in the dorsal root ganglion neurons of rats
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0191032
Abstract: Transient receptor potential vanilloid type 1 (TRPV1) is a polymodal receptor channel that responds to multiple types of stimuli, such as heat, acid, mechanical pressure and some vanilloids. Capsaicin is the most commonly used vanilloid… read more here.
Keywords: ganglion neurons; dorsal root; root ganglion; trpv1 ... See more keywords
Identification of Persistent and Resurgent Sodium Currents in Spiral Ganglion Neurons Cultured from the Mouse Cochlea
Sign Up to like & getrecommendations! Published in 2017 at "eNeuro"
DOI: 10.1523/eneuro.0303-17.2017
Abstract: Abstract In spiral ganglion neurons (SGNs), the afferent single units of the auditory nerve, high spontaneous and evoked firing rates ensure preservation of the temporal code describing the key features of incoming sound. During postnatal… read more here.
Keywords: resurgent; ganglion neurons; auditory nerve; identification persistent ... See more keywords
Sensorineural Hearing Loss and Mitochondrial Apoptosis of Cochlear Spiral Ganglion Neurons in Fibroblast Growth Factor 13 Knockout Mice
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.658586
Abstract: Deafness is known to occur in more than 400 syndromes and accounts for almost 30% of hereditary hearing loss. The molecular mechanisms underlying such syndromic deafness remain unclear. Furthermore, deafness has been a common feature… read more here.
Keywords: hearing loss; ganglion neurons; deafness; spiral ganglion ... See more keywords
Autophagy Regulates the Survival of Hair Cells and Spiral Ganglion Neurons in Cases of Noise, Ototoxic Drug, and Age-Induced Sensorineural Hearing Loss
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.760422
Abstract: Inner ear hair cells (HCs) and spiral ganglion neurons (SGNs) are the core components of the auditory system. However, they are vulnerable to genetic defects, noise exposure, ototoxic drugs and aging, and loss or damage… read more here.
Keywords: hearing loss; ganglion neurons; hair cells; spiral ganglion ... See more keywords
Transcriptional Alterations of Mouse Trigeminal Ganglion Neurons Following Orofacial Inflammation Revealed by Single-Cell Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.885569
Abstract: Orofacial inflammation leads to transcriptional alterations in trigeminal ganglion (TG) neurons. However, diverse alterations and regulatory mechanisms following orofacial inflammatory pain in different types of TG neurons remain unclear. Here, orofacial inflammation was induced by… read more here.
Keywords: inflammation; transcriptional alterations; orofacial inflammation; ganglion neurons ... See more keywords