Ganglioside Hp-s1 Analogue Inhibits Amyloidogenic Toxicity in Alzheimer's Disease Model Cells.
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DOI: 10.1021/acschemneuro.8b00406
Abstract: Alzheimer's disease (AD) is characterized by extracellular deposition of amyloid plaques, which are predominantly composed of amyloid-β (Aβ) peptide derived from amyloid precursor protein (APP) cleavage. APP interacts with tropomyosin receptor kinase A, a neurotrophic… read more here.
Keywords: ganglioside analogue; alzheimer disease; model cells; model ... See more keywords