Two Feet on the Membrane: Uptake of Clostridial Neurotoxins.
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DOI: 10.1007/82_2016_48
Abstract: The extraordinary potency of botulinum neurotoxins (BoNT) and tetanus neurotoxin (TeNT) is mediated by their high neurospecificity, targeting peripheral cholinergic motoneurons leading to flaccid and spastic paralysis, respectively, and successive respiratory failure. Complex polysialo gangliosides… read more here.
Keywords: two feet; feet membrane; ganglioside binding; membrane uptake ... See more keywords