Total Synthesis of the Echinodermatous Ganglioside LLG-3 Possessing the Biological Function of Promoting the Neurite Outgrowth.
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DOI: 10.1021/acs.orglett.0c02692
Abstract: A total synthesis of echinodermatous ganglioside LLG-3 with neuritogenic activity was accomplished by a convergent strategy. The synthesis of 2-hydroxyethyl 8-O-Me-α-sialoside 2 was started from the phenyl 7,8-di-O-Pico-thiosialoside 5, which can be chemoselectively removed the… read more here.
Keywords: ganglioside; synthesis echinodermatous; total synthesis; ganglioside llg ... See more keywords