Insights into Siglec‐7 Binding to Gangliosides: NMR Protein Assignment and the Impact of Ligand Flexibility
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DOI: 10.1002/advs.202415782
Abstract: Gangliosides, sialylated glycosphingolipids abundant in the nervous system, play crucial roles in neurotransmission, interaction with regulatory proteins, cell–cell recognition, and signaling. Altered gangliosides expression has been correlated with pathological processes, including cancer, inflammatory disorders, and… read more here.
Keywords: cancer; gangliosides nmr; binding gangliosides; siglec binding ... See more keywords