Persistent mTORC1 activation due to loss of liver tuberous sclerosis complex 1 promotes liver injury in alcoholic hepatitis.
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DOI: 10.1097/hep.0000000000000373
Abstract: OBJECTIVE The aim of the study is to investigate the role and mechanisms of tuberous sclerosis complex 1 (TSC1) and mechanistic target of rapamycin complex 1 (mTORC1) in alcohol associated liver disease. DESIGN Liver-specific Tsc1… read more here.
Keywords: liver injury; alcohol fed; gao binge; binge alcohol ... See more keywords