Articles with "gap19" as a keyword



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Xentry-Gap19 inhibits Connexin43 hemichannel opening especially during hypoxic injury

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Published in 2020 at "Drug Delivery and Translational Research"

DOI: 10.1007/s13346-020-00763-y

Abstract: Hypoxic injury results in cell death, tissue damage and activation of inflammatory pathways. This is mediated by pathological Connexin43 (Cx43) hemichannel (HC) opening resulting in osmotic and ionic imbalances as well as cytokine production perpetuating… read more here.

Keywords: hemichannel opening; xentry gap19; hypoxic injury; gap19 ... See more keywords