Synthesis of furan-fused 1,4-dihydrocarbazoles via an unusual Garratt-Braverman Cyclization of indolyl propargyl ethers and their antifungal activity
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DOI: 10.1016/j.tet.2018.05.001
Abstract: Abstract The reactivity of indole based bis-propargyl ethers 4a-4g under Garratt-Braverman condition (KOBut in refluxing toluene) has been studied. Interestingly, these propargyl systems with one arm attached with substituted 3-indolyl derivatives leaving the other arm… read more here.
Keywords: propargyl ethers; synthesis furan; furan fused; garratt braverman ... See more keywords
Synthesis of crescent shaped heterocycle-fused aromatics via Garratt-Braverman cyclization and their DNA-binding studies
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DOI: 10.1016/j.tetlet.2017.04.003
Abstract: Three crescent shaped heterocycle-fused phenanthrene based systems 1–3 have been synthesized starting from benzene (or substituted benzene) 1,2-bis-propargyl alcohols. Bis-alkylation with propargylic bromides provided the key intermediate, the bis-propargyl bis-ethers. In spite of the possibility… read more here.
Keywords: heterocycle fused; crescent shaped; garratt braverman; shaped heterocycle ... See more keywords