VGLL3 increases the dependency of cancer cells on de novo nucleotide synthesis through GART expression
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30251
Abstract: Vestigial‐like family member 3 (VGLL3) is a member of the VGLL family that serves as cofactors for TEA‐domain transcription factors. Although VGLL3 is involved in the proliferation of cancer cells, the molecular mechanisms underlying VGLL3‐mediated… read more here.
Keywords: cancer cells; vgll3; proliferation; gart ... See more keywords
GART promotes the proliferation and migration of human non-small cell lung cancer cell lines A549 and H1299 by targeting PAICS-Akt-β-catenin pathway
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1543463
Abstract: Background Lung adenocarcinoma (LUAD) is the primary subtype of Non-small cell lung cancer (NSCLC) and a serious threat to human health. However, the precise molecular mechanisms in lung cancer remain largely unexplored. Methods Herein, we… read more here.
Keywords: lung cancer; gart; cell; paics akt ... See more keywords