Generation and physicochemical characterization of posaconazole cocrystals using Gas Antisolvent (GAS) and Supercritical Solvent (CSS) methods
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Supercritical Fluids"
DOI: 10.1016/j.supflu.2020.105134
Abstract: Abstract Posaconazole (PSZ) is a BCS (biopharmaceutical classification system) Class II anti-fungal drug used to treat infections in immunocompromised patients. The work presented herein describes the generation of cocrystals of PSZ with 4-aminobenzoic acid (4AMB)… read more here.
Keywords: gas antisolvent; gas; antisolvent gas; antisolvent ... See more keywords
Encapsulation of trans-resveratrol in poly(ε-caprolactone) by GAS antisolvent
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Supercritical Fluids"
DOI: 10.1016/j.supflu.2021.105164
Abstract: Abstract In this study, poly(e-caprolactone) particles containing resveratrol were developed employing the GAS antisolvent technique. A central composite design 22 evaluated the influence of polymer, resveratrol mass ratio (2:1, 1:1, 1:2), and pressure (100, 120,… read more here.
Keywords: gas antisolvent; poly caprolactone; encapsulation;
A kinetic modeling of particle formation by gas antisolvent process: Precipitation of aspirin
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Dispersion Science and Technology"
DOI: 10.1080/01932691.2016.1188709
Abstract: ABSTRACT Population balance equations (PBEs) are often integro-partial differential in nature due to complexities involved in nonconventional crystallization processes, especially gas antisolvent (GAS). The reason is that they include phenomena such as primary nucleation, secondary… read more here.
Keywords: precipitation aspirin; process; gas antisolvent; gas ... See more keywords
Experimental Determination of a Chiral Ternary Solubility Diagram and Its Interpretation in Gas Antisolvent Fractionation
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DOI: 10.3390/molecules28052115
Abstract: Although crystallization has been widely applied for the enantiomeric enrichment of non-racemates both in research and in industrial applications, the physical–chemical background of chiral crystallizations is not as frequently discussed. A guide for the experimental… read more here.
Keywords: antisolvent fractionation; solubility; ternary solubility; phase ... See more keywords