Articles with "gasdermin inhibitor" as a keyword



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Gasdermin D inhibitor protects against sepsis

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Published in 2020 at "Nature Reviews Drug Discovery"

DOI: 10.1038/d41573-020-00084-2

Abstract: 388 | JuNe 2020 | volume 19 An expansion of neutrophils in patients with cancer is usually associated with a poor prognosis. This is thought to be due to the ability of neutrophils to induce… read more here.

Keywords: tumour cells; netosis; gasdermin inhibitor; cell ... See more keywords

Gasdermin D Inhibitor Necrosulfonamide Alleviates Angiotensin II-Induced Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice

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Published in 2024 at "Biomolecules"

DOI: 10.3390/biom14060726

Abstract: Abdominal aortic aneurysm (AAA) is a chronic aortic disease that lacks effective pharmacological therapies. This study was performed to determine the influence of treatment with the gasdermin D inhibitor necrosulfonamide on experimental AAAs. AAAs were… read more here.

Keywords: mice; inhibitor necrosulfonamide; gasdermin inhibitor; abdominal aortic ... See more keywords