Association of Gastric Acid Suppression With Recurrent Clostridium difficile Infection: A Systematic Review and Meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Internal Medicine"
DOI: 10.1001/jamainternmed.2017.0212
Abstract: Importance Gastric acid suppression has been associated with an increased risk of primary Clostridium difficile infection (CDI), but the risk of recurrent CDI in patients taking gastric acid suppressant medications is unclear. Objective To perform… read more here.
Keywords: acid suppression; acid; recurrent cdi; gastric acid ... See more keywords
Withholding Proton Pump Inhibitors to Prevent Recurrent Clostridium difficile: Time for a Randomized Trial.
Sign Up to like & getrecommendations! Published in 2017 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2017.0233
Abstract: Clostridium difficile causes almost half a million infections annually among hospitalized and community-dwelling patients in the United States, and approximately 1 in 5 patients will develop arecurrentCdifficile infection.1 Therefore, identificationofmodifiable risk factors for incident and… read more here.
Keywords: medicine; difficile; infection; acid suppressants ... See more keywords
Gastric acid secretion and gastrin release during continuous vagal neuromonitoring in thyroid surgery
Sign Up to like & getrecommendations! Published in 2017 at "Langenbeck's Archives of Surgery"
DOI: 10.1007/s00423-017-1555-z
Abstract: PurposeThe vagus nerve (VN) has essential regulatory roles in the gastric acid secretion and gastrin release. Continuous intraoperative neuromonitoring (CIONM) via VN stimulation is a promising technique in thyroid surgery because it potentially avoids injury… read more here.
Keywords: gastrin; acid secretion; cionm; gastric acid ... See more keywords
NERP-2 regulates gastric acid secretion and gastric emptying via the orexin pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.02.064
Abstract: Neuroendocrine regulatory peptide (NERP)-2 is derived from a distinct region of VGF, a neurosecretory protein originally identified as a product of a nerve growth factor-responsive gene in rat PC12 cells. Colocalization of NERP-2 with orexin-A in… read more here.
Keywords: nerp; secretion gastric; gastric emptying; acid secretion ... See more keywords
Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.04.003
Abstract: Gastric acid secretion by parietal cells requires trafficking and exocytosis of H/K-ATPase-rich tubulovesicles (TVs) toward apical membranes in response to histamine stimulation via cyclic AMP elevation. Here, we found that TRPML1 (ML1), a protein that… read more here.
Keywords: acid secretion; parietal cells; acid; gastric acid ... See more keywords
Na+-K+-2Cl- cotransporter 2 located in the human and murine gastric mucosa is involved in secretagogue-induced gastric acid secretion and is downregulated in lipopolysaccharide-treated mice.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173162
Abstract: Na+-K+-2Cl- cotransporter (NKCC) is expressed at exceptionally high levels in gastric parietal cells. Bumetanide, a potent loop diuretic that blocks NKCC, usually causes a decrease in gastric acid secretion. Endotoxaemia causes hypochlorhydria in vivo, in… read more here.
Keywords: secretion; gastric mucosa; acid secretion; treated mice ... See more keywords
[Gastric acid rebound after a proton pump inhibitor: Narrative review of literature].
Sign Up to like & getrecommendations! Published in 2018 at "Therapie"
DOI: 10.1016/j.therap.2017.08.005
Abstract: BACKGROUND Since the introduction of the first proton pump inhibitor (PPI) 20 years ago, studies have examined the presence of a rebound effect when this treatment is discontinued. These studies are heterogeneous and contradictory: the last… read more here.
Keywords: literature; rebound; acid rebound; proton pump ... See more keywords
Bitter Peptides YFYPEL, VAPFPEVF, and YQEPVLGPVRGPFPIIV, Released during Gastric Digestion of Casein, Stimulate Mechanisms of Gastric Acid Secretion via Bitter Taste Receptors TAS2R16 and TAS2R38
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Agricultural and Food Chemistry"
DOI: 10.1021/acs.jafc.2c05228
Abstract: Eating satiating, protein-rich foods is one of the key aspects of modern diet, although a bitter off-taste often limits the application of some proteins and protein hydrolysates, especially in processed foods. Previous studies of our… read more here.
Keywords: mechanisms gastric; gastric acid; stimulate mechanisms; secretion ... See more keywords
Mucoadhesive Hydrogel with Anti-gastric Acid and Sustained-Release Functions for Amelioration of DSS-Induced Ulcerative Colitis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c07777
Abstract: Mucoadhesive hydrogels with multifunctional properties such as gastric acid resistance and sustained drug release in the intestinal tract are highly desirable for the oral treatment of inflammatory bowel diseases (IBDs). Polyphenols are proven to have… read more here.
Keywords: gas; gas hydrogel; hydrogel; gastric acid ... See more keywords
Identification of Bitter-Taste Intensity and Molecular Weight as Amino Acid Determinants for the Stimulating Mechanisms of Gastric Acid Secretion in Human Parietal Cells in Culture.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.8b01802
Abstract: Secretion of gastric acid, aimed at preventing bacterial growth and aiding the digestion of foods in the stomach, is chiefly stimulated by dietary intake of protein and amino acids (AAs). However, AAs' key structural determinants… read more here.
Keywords: acid secretion; secretion; gastric acid; bitter taste ... See more keywords
Tea Polyphenol Liposomes Overcome Gastric Mucus to Treat Helicobacter Pylori Infection and Enhance the Intestinal Microenvironment.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c23342
Abstract: Infection with Helicobacter pylori (Hp) is one of the leading causes of stomach cancer. The ability to treat Hp infection is hampered by a lack of stomach gastric acid environment. This work introduces a nanoliposome… read more here.
Keywords: gastric acid; infection; treat; tea polyphenol ... See more keywords