Association of Intensive Endoscopic Screening Burden With Gastric Cancer Detection
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DOI: 10.1001/jamanetworkopen.2020.32542
Abstract: Key Points Question Is monthly variation in gastric cancer screening rates associated with changes in rates of cancer detection? Findings This cohort study of 21 535 222 participants from the Korean National Cancer Screening Program database found… read more here.
Keywords: gastric cancer; cancer detection; association intensive; cancer ... See more keywords
Assessment of Lymph Node Metastasis in Patients With Gastric Cancer to Identify Those Suitable for Middle Segmental Gastrectomy
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DOI: 10.1001/jamanetworkopen.2021.1840
Abstract: Key Points Question Can metastasis at key lymph node (LN) stations be used to inform surgical management in patients with gastric cancer? Findings In this cohort study of 9952 patients who underwent surgery for gastric… read more here.
Keywords: gastric cancer; lymph node; cancers station; 1m0 cancers ... See more keywords
Global Incidence and Mortality of Gastric Cancer, 1980-2018
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DOI: 10.1001/jamanetworkopen.2021.18457
Abstract: Key Points Question Is the global burden of gastric cancer increasing in younger adults compared with older adults? Findings In this cohort study of data from 1980 to 2018 covering more than 1 million cases… read more here.
Keywords: incidence; 1980 2018; gastric cancer; mortality ... See more keywords
Assessment of Outcomes From 1-Year Surveillance After Detection of Early Gastric Cancer Among Patients at High Risk in Japan
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DOI: 10.1001/jamanetworkopen.2022.27667
Abstract: Key Points Question Is new gastric cancer (GC) detectable approximately 1 year after intensive index endoscopic examination using both white light and narrow-band imaging among patients with a high risk of GC? Findings In this… read more here.
Keywords: year; patients high; high risk; gastric cancer ... See more keywords
Whole-Exome Sequencing Among Chinese Patients With Hereditary Diffuse Gastric Cancer
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DOI: 10.1001/jamanetworkopen.2022.45836
Abstract: Key Points Questions What is the incidence rate of germline alterations in CDH1, which has been reported as a susceptibility gene present in 25% to 50% of patients with hereditary diffuse gastric cancer (HDGC), and… read more here.
Keywords: germline alterations; patients hereditary; hereditary diffuse; gastric cancer ... See more keywords
Finding Lymph Nodes With Carbon Nanoparticle Suspension Injection.
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DOI: 10.1001/jamanetworkopen.2022.7759
Abstract: Taking into account that the stage of the disease at the time of diagnosis is considered to be one of the main factors in long-term survival among patients with gastric cancer, an adequate clinical evaluation,… read more here.
Keywords: cnsi; lns; gastric cancer; nanoparticle suspension ... See more keywords
Combined Surgery and Extensive Intraoperative Peritoneal Lavage vs Surgery Alone for Treatment of Locally Advanced Gastric Cancer: The SEIPLUS Randomized Clinical Trial.
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DOI: 10.1001/jamasurg.2019.0153
Abstract: Importance Peritoneal metastasis is the most frequent pattern of postoperative recurrence in patients with gastric cancer. Extensive intraoperative peritoneal lavage (EIPL) is a new prophylactic strategy for treatment of peritoneal metastasis of locally advanced gastric… read more here.
Keywords: surgery; advanced gastric; gastric cancer; surgery plus ... See more keywords
Short-term Outcomes of Robotic Gastrectomy vs Laparoscopic Gastrectomy for Patients With Gastric Cancer: A Randomized Clinical Trial.
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DOI: 10.1001/jamasurg.2021.3182
Abstract: Importance Robotic gastrectomy (RG) for gastric cancer may be associated with decreased incidence of intra-abdominal infectious complications, including pancreatic fistula, leakage, and abscess. Prospective randomized clinical trials comparing laparoscopic gastrectomy (LG) and RG are thus… read more here.
Keywords: incidence; gastric cancer; gastrectomy; group ... See more keywords
Association Between Hereditary Lobular Breast Cancer Due to CDH1 Variants and Gastric Cancer Risk.
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DOI: 10.1001/jamasurg.2021.5118
Abstract: Importance Hereditary cancer risk is informed by the presence of a germline gene variant more so than by family history of cancer. Objective To assess gastric cancer risk among patients who received a diagnosis of… read more here.
Keywords: breast; gastric cancer; family; history ... See more keywords
Surgical Management of Gastric Cancer: A Review.
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DOI: 10.1001/jamasurg.2022.0182
Abstract: Importance Surgery plays a critical role in the management of all stages of gastric cancer. Observations For patients with early gastric cancer and low risk of lymph node metastasis, endoscopic therapy or surgery alone is… read more here.
Keywords: cancer; surgery; therapy; management gastric ... See more keywords
Cisplatin‐resistant cancer cells are sensitive to Aurora kinase A inhibition by alisertib
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DOI: 10.1002/1878-0261.12066
Abstract: De novo and acquired resistance to platinum therapy such as cisplatin (CDDP) is a clinical challenge in gastric cancer treatment. Aberrant expression and activation of aurora kinase A (AURKA) and eukaryotic translation initiation factor 4E… read more here.
Keywords: gastric cancer; resistance; cddp; aurora kinase ... See more keywords