Differential regulation analysis reveals dysfunctional regulatory mechanism involving transcription factors and microRNAs in gastric carcinogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Artificial intelligence in medicine"
DOI: 10.1016/j.artmed.2017.02.006
Abstract: Gastric cancer (GC) is one of the most incident malignancies in the world. Although lots of featured genes and microRNAs (miRNAs) have been identified to be associated with gastric carcinogenesis, underlying regulatory mechanisms still remain… read more here.
Keywords: analysis; differential regulation; gastric carcinogenesis; genes mirnas ... See more keywords
Network construction of gastric microbiome and organization of microbial modules associated with gastric carcinogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48925-4
Abstract: In addition to Helicobacter pylori infection, nitrosating/nitrate-reducing bacteria and type IV secretion system (T4SS) protein gene-contributing bacteria have been proposed as potential causes of gastric cancer development. However, bacterial modules related with gastric carcinogenesis have… read more here.
Keywords: network; microbial modules; microbiome; gastric microbiome ... See more keywords
Helicobacter pylori infection‐induced H3Ser10 phosphorylation in stepwise gastric carcinogenesis and its clinical implications
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DOI: 10.1111/hel.12486
Abstract: Our previous works have demonstrated that Helicobacter pylori (Hp) infection can alter histone H3 serine 10 phosphorylation status in gastric epithelial cells. However, whether Helicobacter pylori‐induced histone H3 serine 10 phosphorylation participates in gastric carcinogenesis… read more here.
Keywords: helicobacter pylori; pylori infection; phosphorylation; gastric carcinogenesis ... See more keywords
Mucosal microbiome dysbiosis in gastric carcinogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Gut"
DOI: 10.1136/gutjnl-2017-314281
Abstract: Objectives We aimed to characterise the microbial changes associated with histological stages of gastric tumourigenesis. Design We performed 16S rRNA gene analysis of gastric mucosal samples from 81 cases including superficial gastritis (SG), atrophic gastritis… read more here.
Keywords: dysbiosis; mucosal microbiome; mucosal; microbiome dysbiosis ... See more keywords
Association between sarcopenia and gastric carcinogenesis: A health check-up cohort study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.4_suppl.46
Abstract: 46 Background: Insulin resistance which is a mechanism of metabolic syndrome has been known to promote carcinogenesis of various malignancies. In addition, metabolic syndrome is associated with sarcopenia. Thus, the aim was to investigate the… read more here.
Keywords: carcinogenesis; sarcopenia gastric; gastric carcinogenesis; association sarcopenia ... See more keywords
DNMT1 overexpression predicting gastric carcinogenesis, subsequent progression and prognosis: a meta and bioinformatic analysis
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DOI: 10.18632/oncotarget.21480
Abstract: DNMT1 is important in maintaining DNA methylation, and participates in the oncogenesis via up- or down-regulation leading to hyper-methylation or hypo-methylation. In the meta and bioinformatic analysis, we found that DNMT1 expression was higher in… read more here.
Keywords: expression; dnmt1; gastric carcinogenesis; meta bioinformatic ... See more keywords
Nrf2 Downregulation Contributes to Epithelial-to-Mesenchymal Transition in Helicobacter pylori-Infected Cells
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DOI: 10.3390/cancers14174316
Abstract: Simple Summary Gastric cancer is mainly linked to Helicobacter pylori infection. It is therefore important to decipher the mechanisms involved in H. pylori-induced gastric carcinogenesis, and especially the early events. We have previously demonstrated that… read more here.
Keywords: pylori infection; infection; epithelial mesenchymal; helicobacter pylori ... See more keywords
Anti-Inflammatory and Antioxidant Effects of Carvacrol on N-Methyl-N′-Nitro-N-Nitrosoguanidine (MNNG) Induced Gastric Carcinogenesis in Wistar Rats
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14142848
Abstract: Carvacrol is a dietary polyphenol from Lamiaceae plants that has been shown to possess a wide range of biological activities including antioxidant and antitumor effects. This study aimed to investigate its anti-inflammatory and antioxidant effects… read more here.
Keywords: carvacrol; anti inflammatory; mnng; wistar rats ... See more keywords