Bcl‐2/Bcl‐xl inhibitor APG‐1252‐M1 is a promising therapeutic strategy for gastric carcinoma
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DOI: 10.1002/cam4.3090
Abstract: Gastric carcinoma is the third major cause of cancer‐related death in China. Bcl‐2 and other BH3 family proteins are critically important in the process of apoptosis pathway, which may be a promising target. APG‐1252‐M1 specifically… read more here.
Keywords: gastric carcinoma; antitumor effect; bcl bcl; apg 1252 ... See more keywords
Genetic features of multicentric/multifocal intramucosal gastric carcinoma
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DOI: 10.1002/ijc.31578
Abstract: Chronic gastritis caused by Helicobacter pylori (H. pylori) infection could lead to the development of gastric cancer. The finding that multiple gastric cancers can develop synchronously and/or metachronously suggests the development of field cancerization in… read more here.
Keywords: gastric carcinomas; multiple intramucosal; gastric carcinoma; intramucosal ... See more keywords
Bridging genomics and phenomics of gastric carcinoma
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DOI: 10.1002/ijc.32228
Abstract: Genetic alterations are the starting point leading to numerous changes in clinical and pathologic features (phenotypes) of individual cancers; however, their inter‐relationships in gastric cancers (GC) are unclear. We performed massive parallel sequencing of 381… read more here.
Keywords: gastric carcinoma; genomics phenomics; bridging genomics; genetic alterations ... See more keywords
Clinical Outcomes and Prognostic Factors in Gastric Carcinoma Patients with Curative Surgery Followed by Adjuvant Treatment: Real-World Scenario
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DOI: 10.1007/s12029-020-00440-w
Abstract: Background A wide range of adjuvant treatment regimens exist in gastric carcinoma patients which include chemotherapy, radiotherapy, and/or both either sequential or concurrent. The study aimed to assess the benefit of adjuvant sequential chemotherapy followed… read more here.
Keywords: gastric carcinoma; surgery followed; prognostic factors; followed adjuvant ... See more keywords
Late recurrence of gastric carcinoma 15 years after surgery
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DOI: 10.1007/s12328-020-01143-2
Abstract: A 70-year-old man who had undergone total gastrectomy 15 years ago for mucinous gastric carcinoma on the lesser curvature of the cardia, visited our hospital complaining of cough. Chest X-ray showed a right hilar shadow… read more here.
Keywords: gastric carcinoma; late recurrence; recurrence; recurrence gastric ... See more keywords
Etiologic and Clinicopathological Correlates of Gastric Carcinoma in the Egyptian Delta
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DOI: 10.1007/s13193-018-0754-6
Abstract: We aimed at evaluation of the clinicoepidemiologic data of patients with gastric carcinoma in the Egyptian Delta as regards the etiologic factors, behavior, presenting symptoms, and tumor location, grade, and stage with highlighting of the… read more here.
Keywords: gastric carcinoma; oncology; egyptian delta; carcinoma egyptian ... See more keywords
MicroRNA-128 contributes to the progression of gastric carcinoma through GAREM-mediated MAPK signaling activation.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.08.177
Abstract: Gastric carcinoma (GC) represents the most common malignant cancer and the second leading cause of cancer death worldwide. However, the molecular mechanisms and biological progression of GC remain unknown. In this study, we found that… read more here.
Keywords: gastric carcinoma; progression; mir 128; mapk signaling ... See more keywords
Adjuvant chemoradiation for gastric carcinoma: State of the art and perspectives
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DOI: 10.1016/j.ctro.2018.02.005
Abstract: An estimated 990,000 new cases of gastric cancer are diagnosed worldwide each year. Surgical excision, the only chance for prolonged survival, is feasible in about 20% of cases. Even after surgery, the median survival is… read more here.
Keywords: gastric carcinoma; carcinoma state; art perspectives; chemoradiation gastric ... See more keywords
NAE modulators: A potential therapy for gastric carcinoma.
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DOI: 10.1016/j.ejmech.2022.114156
Abstract: Neural precursor cell expressed developmentally downregulated protein-8 (NEDD8) is a ubiquitin-like protein, which activates an important post-translational modification process: neddylation, thereby regulating the stability and degradation of various proteins related to multiple physiological processes. And… read more here.
Keywords: modulators potential; gastric carcinoma; anti tumor; nae modulators ... See more keywords
Selective oncolytic effect in Epstein-Barr virus (EBV)-associated gastric carcinoma through efficient lytic induction by Euphorbia extracts
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DOI: 10.1016/j.jff.2018.01.004
Abstract: Abstract Lytic induction of latent Epstein-Barr virus (EBV) has been considered as a therapeutic approach for efficient treatment of EBV-associated malignancies. Here, we established a robust assay system quantitatively measuring EBV lytic induction and identified… read more here.
Keywords: gastric carcinoma; ebv; ebv associated; lytic induction ... See more keywords
Aberrant Expression of Gastric Carcinoma High Expressed Transcript 1 is a Diagnostic and Prognostic Biomarker in Human Cancer.
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DOI: 10.1016/j.jnma.2020.05.017
Abstract: BACKGROUND Gastric carcinoma high expressed transcript 1 (GHET1), a long noncoding RNA (LncRNA), has been reported to be involved in tumor genesis and cancer progression. High GHET1 expression is correlated with a poor prognosis in… read more here.
Keywords: gastric carcinoma; expressed transcript; carcinoma high; expression ... See more keywords