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   Articles with "gastric conditions" as a keyword



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The Oral Bioavailability and Effect of Various Gastric Conditions on the Pharmacokinetics of Dersimelagon in Healthy Adult Volunteers

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recommendations! Published in 2023 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.1235

Abstract: Dersimelagon is a novel orally administered selective agonist for melanocortin receptor 1 being investigated for the treatment of erythropoietic protoporphyria, X‐linked protoporphyria, and diffuse cutaneous systemic sclerosis. In this open‐label, multicenter, randomized, two‐cohort, sequential crossover… read more here.

Keywords: oral bioavailability; various gastric; bioavailability; effect various ... See more keywords
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Accurate and sensitive determination of sildenafil, tadalafil, vardenafil, and avanafil in illicit erectile dysfunction medications and human urine by LC with quadrupole-TOF-MS/MS and their behaviors in simulated gastric conditions.

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recommendations! Published in 2019 at "Journal of separation science"

DOI: 10.1002/jssc.201800734

Abstract: The widespread use of phosphodiesterase-5 inhibitors has attracted broad attention of counterfeiters to develop illicit erectile products with inaccurate amounts, unknown toxicity, and purity of active ingredients. Correspondingly, intake of these products endangers consumer health… read more here.

Keywords: human urine; medications human; determination; gastric conditions ... See more keywords
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A pectin-gelatin gel containing oral rehydration solution and the release of sodium chloride under simulated gastric conditions.

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recommendations! Published in 2019 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2019.06.146

Abstract: Both gelatin and pectin have the ability to trap salt and facilitate its release under simulated gastric conditions. The objective of this study was to develop a pectin-gelatin gel fortified with oral rehydration solution/s (ORS)… read more here.

Keywords: pectin gelatin; salt; gastric conditions; gel ... See more keywords