Isolation of Mouse Primary Gastric Epithelial Cells to Investigate the Mechanisms of Helicobacter pylori Associated Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7568-6_10
Abstract: The gastrointestinal epithelium provides the first line of defense against invading pathogens, among which Helicobacter pylori is linked to numerous gastric pathologies, including chronic gastritis and cancer. Primary gastric epithelial cells represent a useful model for… read more here.
Keywords: gastric epithelial; epithelial cells; primary gastric; pylori associated ... See more keywords
Exploiting the Gastric Epithelial Barrier: Helicobacter pylori's Attack on Tight and Adherens Junctions.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/978-3-319-50520-6_9
Abstract: Highly organized intercellular tight and adherens junctions are crucial structural components for establishing and maintenance of epithelial barrier functions, which control the microbiota and protect against intruding pathogens in humans. Alterations in these complexes represent… read more here.
Keywords: gastric epithelial; adherens junctions; tight adherens; epithelial barrier ... See more keywords
AntogomiR-451 protects human gastric epithelial cells from ethanol via activating AMPK signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.02.082
Abstract: The prevention and treatment efficiency of ethanol-induced gastric epithelial injury are not satisfied. We have previously shown that AMP-activated protein kinase (AMPK) activation exerts a pro-survival function in human gastric epithelial cells (GECs). miroRNA-451 ("miR-451")'s… read more here.
Keywords: gastric epithelial; epithelial cells; antagomir 451; ampk activation ... See more keywords
Rabeprazole Suppresses Cell Proliferation in Gastric Epithelial Cells by Targeting STAT3-mediated Glycolysis.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114525
Abstract: The dysregulation of glycolysis leads to serials of disease. Rabeprazole is a representative of proton pump inhibitors and widely used in anti-ulcer treatment. However, the function of Rabeprazole on glycolysis in gastric epithelial cells remained… read more here.
Keywords: gastric epithelial; glycolysis; cell proliferation; rabeprazole ... See more keywords
Deoxycholic acid-stimulated macrophage-derived exosomes promote intestinal metaplasia and suppress proliferation in human gastric epithelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173566
Abstract: The crosstalk between macrophages and gastric epithelial cells has emerged as a player in chronic inflammation during intestinal metaplasia. However, the role of bile acid on this modulation remains to be studied. We hypothesized that… read more here.
Keywords: gastric epithelial; intestinal metaplasia; epithelial cells; metaplasia ... See more keywords
Astaxanthin inhibits Helicobacter pylori-induced hyper-proliferation in gastric epithelial cells
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.314
Abstract: Helicobacter pylori (H. pylori) causes peptic ulcer disease, gastritis and gastric adenocarcinoma in gastric epithelial cells. Hyper-proliferation is observed in the mucosa of H. pylori-infected patients. H. pylori stimulates production of reactive oxygen species (ROS),… read more here.
Keywords: gastric epithelial; epithelial cells; hyper proliferation; pylori induced ... See more keywords
The effect of trimethylamine N‐oxide on Helicobacter pylori‐induced changes of immunoinflammatory genes expression in gastric epithelial cells
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2016.11.032
Abstract: &NA; Colonization of Helicobacter pylori (H. pylori) induces immune and inflammatory response in gastric mucosa. Trimethylamine N‐oxide (TMAO), from diet and metabolite through the action of gut microbiota, has been linked to inflammatory diseases. To… read more here.
Keywords: immunoinflammatory genes; gastric epithelial; expression; helicobacter pylori ... See more keywords
Lipopolysaccharide-induced DC-SIGN/TLR4 crosstalk activates NLRP3 inflammasomes via MyD88-independent signaling in gastric epithelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112292
Abstract: Abnormal pattern recognition receptor (PRR) signaling plays an important role in gastric mucosal damage caused by stomach microbiota; however, the underlying molecular mechanisms remain obscure. Here, we show that DC-SIGN, a surface phenotype marker of… read more here.
Keywords: gastric epithelial; epithelial cells; myd88 independent; induced sign ... See more keywords
Hydrotalcite Can Prevent the Damaging Effects of Helicobacter Pylori on Gastric Epithelial Cells
Sign Up to like & getrecommendations! Published in 2018 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927618000314
Abstract: Abstract Background: Helicobacter pylori is a major cause of gastric diseases including gastric cancer. This study was aimed to explore whether hydrotalcite can inhibit H. pylori infection of gastric epithelial cells. Methods: the gastric epithelial… read more here.
Keywords: gastric epithelial; microscopy; pylori infection; helicobacter pylori ... See more keywords
NKX6.3 Regulates Reactive Oxygen Species Production by Suppressing NF-kB and DNMT1 Activities in Gastric Epithelial Cells
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DOI: 10.1038/s41598-017-02901-y
Abstract: NKX6.3 plays an important role in gastric epithelial differentiation and also acts as a gastric tumor suppressor. The specific aim of this study was to determine whether NKX6.3 contributes to gastric mucosal barrier function by… read more here.
Keywords: reactive oxygen; gastric epithelial; production; oxygen species ... See more keywords
Traction method versus conventional endoscopic submucosal dissection for gastric epithelial neoplasms
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029172
Abstract: Abstract Introduction: Endoscopic submucosal dissection (ESD) is an advanced therapeutic technique for en bloc resection of superficial gastrointestinal neoplasms. Although gastric ESD is minimally invasive and provides favorable outcomes, it is technically difficult and requires… read more here.
Keywords: time; esd; traction; procedure time ... See more keywords