Tristetraprolin prevents gastric metaplasia in mice by suppressing pathogenic inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and molecular gastroenterology and hepatology"
DOI: 10.1016/j.jcmgh.2021.07.015
Abstract: BACKGROUND & AIMS Aberrant immune activation is associated with numerous inflammatory and autoimmune diseases and contributes to cancer development and progression. Within the stomach, inflammation drives a well-established sequence from gastritis to metaplasia, eventually resulting… read more here.
Keywords: gastric inflammation; metaplasia; inflammation; ttp ... See more keywords
Nardilysin regulates inflammation, metaplasia, and tumors in murine stomach
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43052
Abstract: Chronic inflammation contributes to a wide variety of human disorders. In the stomach, longstanding gastritis often results in structural alterations in the gastric mucosa, including metaplastic changes and gastric cancers. Therefore, it is important to… read more here.
Keywords: gastric inflammation; regulates inflammation; inflammation; murine stomach ... See more keywords
Glucocorticoids and androgens protect from gastric metaplasia by suppressing group 2 innate lymphoid cell activation.
Sign Up to like & getrecommendations! Published in 2021 at "Gastroenterology"
DOI: 10.1053/j.gastro.2021.04.075
Abstract: BACKGROUND AND AIMS The immune compartment is critical for maintaining tissue homeostasis. A weak immune response increases susceptibility to infection, but immune hyperactivation causes tissue damage, and chronic inflammation may lead to cancer development. In… read more here.
Keywords: gastric inflammation; metaplasia; glucocorticoids androgens; inflammation ... See more keywords
Morphine use induces gastric microbial dysbiosis driving gastric inflammation through TLR2 signalling which is attenuated by proton pump inhibition
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.16025
Abstract: Opioids are the standard drug for pain management; however, their effects on gastric dysfunction are relatively understudied. Opioid users have a higher incidence of gastric pathology leading to increased hospitalization. Herein, we investigated the consequences… read more here.
Keywords: proton pump; pump inhibition; pathology; gastric inflammation ... See more keywords
Positive Selection of Mutations in the Helicobacter pylori katA 5′ Untranslated Region in a Mongolian Gerbil Model of Gastric Disease
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DOI: 10.1128/iai.00004-22
Abstract: To evaluate potential effects of gastric inflammation on Helicobacter pylori diversification and evolution within the stomach, we experimentally infected Mongolian gerbils with an H. pylori strain in which Cag type IV secretion system (T4SS) activity… read more here.
Keywords: helicobacter pylori; t4ss activity; activity; gastric inflammation ... See more keywords
Helicobacter-induced gastric inflammation alters the properties of gastric tissue stem/progenitor cells
Sign Up to like & getrecommendations! Published in 2017 at "BMC Gastroenterology"
DOI: 10.1186/s12876-017-0706-6
Abstract: BackgroundAlthough Helicobacter-induced gastric inflammation is the major predisposing factor for gastric carcinogenesis, the precise mechanism by which chronic gastritis causes gastric cancer remains unclear. Intestinal and spasmolytic polypeptide-expressing metaplasia (SPEM) is considered as precancerous lesions,… read more here.
Keywords: gastric inflammation; tissue stem; inflammation; stem progenitor ... See more keywords
Genistein attenuated gastric inflammation and apoptosis in Helicobacter pylori-induced gastropathy in rats
Sign Up to like & getrecommendations! Published in 2020 at "BMC Gastroenterology"
DOI: 10.1186/s12876-020-01555-x
Abstract: Background Helicobacter pylori ( H. pylori ) infection is a major cause of chronic gastritis, peptic ulcer diseases and cancer. Genistein (4′,5,7-trihydroxyisoflavone), a tyrosine-specific-protein kinase inhibitor, has been shown to exert an anti-inflammatory property .… read more here.
Keywords: gastric inflammation; apoptosis; histopathology; group ... See more keywords
Can mean platelet volume IndIcate HelIcobacter posItIvIty and severIty of gastrIc InflammatIon? An orIgInal study and revIew of the lIterature
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DOI: 10.20471/acc.2019.58.04.02
Abstract: SUMMARY Helicobacter pylori (H. pylori) is a common problem and a significant cause of chronic gastric inflammation. H. pylori, ongoing gastric inflammation and its severity are the most critical component of precursors of gastric cancer.… read more here.
Keywords: gastric inflammation; volume; inflammation; study ... See more keywords