Organoids as a Model to Study Infectious Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7604-1_8
Abstract: The advent of the gastric organoid culture system has provided a new model to emulate native epithelial tissue in vitro. Gastric organoids grow from isolated epithelial stem cells and develop into three dimensional structures that… read more here.
Keywords: infectious disease; model study; study infectious; model ... See more keywords
Gastric organoids—an in vitro model system for the study of gastric development and road to personalized medicine
Sign Up to like & getrecommendations! Published in 2020 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-020-00662-2
Abstract: Gastric cancer ranks as the fifth most common human malignancy and the third leading cause of cancer related deaths. Depending on tumor stage, endoscopic or surgical resection supported by perioperative chemotherapy is the only curative… read more here.
Keywords: medicine; vitro model; organoids vitro; development ... See more keywords
SARS-CoV-2 infection and replication in human gastric organoids
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-26762-2
Abstract: COVID-19 typically manifests as a respiratory illness, but several clinical reports have described gastrointestinal symptoms. This is particularly true in children in whom gastrointestinal symptoms are frequent and viral shedding outlasts viral clearance from the… read more here.
Keywords: infection replication; infection; sars cov; cov infection ... See more keywords
Modeling of COVID-19 disease disparity in gastric organoids reveals the spatiotemporal dynamics of SARS-CoV-2 infectivity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjac007
Abstract: Dear Editor, The promptness and continuous expansion of the coronavirus disease 2019 (COVID-19) pandemic, elicited by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants, has presented an unprecedented impact on human health (WHO… read more here.
Keywords: disease; infection; sars cov; gastric organoids ... See more keywords