Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump.
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DOI: 10.1021/acs.jmedchem.2c00338
Abstract: As specific inhibitors of the gastric proton pump, responsible for gastric acidification, K+-competitive acid blockers (P-CABs) have recently been utilized in the clinical treatment of gastric acid-related diseases in Asia. However, as these compounds have… read more here.
Keywords: acid blockers; proton pump; gastric proton; competitive acid ... See more keywords