Intestinal Gastrin/CCKBR Axis Protects against Type 2 Diabetes by Reducing Intestinal Glucose Absorption through the PI3K/Akt/eIF4B Signaling Pathway
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202410032
Abstract: The Gastrin/CCKBR axis is essential for inhibiting intestinal sodium absorption, but its effects on intestinal glucose metabolism remain elusive. This study aims to determine the role of intestinal Gastrin/CCKBR on glucose absorption in the development… read more here.
Keywords: gastrin cckbr; intestinal glucose; cckbr; gastrin ... See more keywords
Exendin‐4(Lys27PAL)/gastrin/xenin‐8‐Gln: A novel acylated GLP‐1/gastrin/xenin hybrid peptide that improves metabolic status in obese‐diabetic (ob/ob) mice
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3106
Abstract: Therapeutic benefits of peptide‐based drugs is limited by rapid renal elimination. read more here.
Keywords: gastrin; exendin lys27pal; gastrin xenin; lys27pal gastrin ... See more keywords
Gastric acid secretion and gastrin release during continuous vagal neuromonitoring in thyroid surgery
Sign Up to like & getrecommendations! Published in 2017 at "Langenbeck's Archives of Surgery"
DOI: 10.1007/s00423-017-1555-z
Abstract: PurposeThe vagus nerve (VN) has essential regulatory roles in the gastric acid secretion and gastrin release. Continuous intraoperative neuromonitoring (CIONM) via VN stimulation is a promising technique in thyroid surgery because it potentially avoids injury… read more here.
Keywords: gastrin; acid secretion; cionm; gastric acid ... See more keywords
GLI-fully Responsive to Inflammatory Cytokines
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2021.02.001
Abstract: hronic Helicobacter pylori infection is a primary risk Cfactor for the development of gastric cancer, a leading cause of cancer-related death worldwide. H pylori initially colonizes the gastric antrum and, over time, can spread throughout… read more here.
Keywords: gastrin; hedgehog signaling; gastroenterology; cell ... See more keywords
Gastrin for prevention of steroid-associated osteonecrosis in rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of orthopaedic translation"
DOI: 10.1016/j.jot.2020.02.008
Abstract: Summary Background/Objective Steroid-associated osteonecrosis (SAON) mostly occurs in large joints such as hip that finally results in joint collapse and replacement. An effective strategy for preventing SAON is inhibition of bone resorption and lipid formation,… read more here.
Keywords: osteonecrosis; gastrin; associated osteonecrosis; bone ... See more keywords
Sporadic, non‐functional, gastrin‐producing duodenal neuroendocrine tumors: A retrospective study of an infrequent disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Digestive Diseases"
DOI: 10.1111/1751-2980.13129
Abstract: Non‐functioning gastrin‐producing neuroendocrine neoplasms (NEN) of the duodenum are rare gastrointestinal tumors without a clinical syndrome due to gastrin production. Their incidence has significantly increased as an incidental finding during endoscopic studies. The aim of… read more here.
Keywords: gastrin; non functional; gastrin producing; functional gastrin ... See more keywords
Abstract 262: Gastrin-dependent suppression of CCK2R+ antrum stem cells inhibits gastric atrophy and cancer initiation in C57BL/6 mice
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-262
Abstract: Background The cholecystokin-2/gastrin receptor (CCK2R) is expressed by rare epithelial cells in the gastric antrum that are bone fide +4 gastric stem cells. CCK2R+ antral stem cells are relatively quiescent, divide asymmetrically, and lineage trace… read more here.
Keywords: cancer; cck2r; stem; stem cells ... See more keywords
Gastrin for the treatment of acute graft-versus-host disease of the stomach
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-4084
Abstract: Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative therapy for many hematological malignancies. However, its success is frequently compromised by acute graft-versus-host disease (aGVHD), a severe complication driven by allogeneic T cell-mediated organ damage.… read more here.
Keywords: treatment; agvhd; stomach; cell ... See more keywords
Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Medicine"
DOI: 10.1186/s10020-021-00352-w
Abstract: Background It is known that increased gastrin concentration is negatively correlated with cardiovascular mortality, and plasma gastrin levels are increased in patients after myocardial infarction (MI). However, whether gastrin can play a protective role in… read more here.
Keywords: protective effect; myocardial infarction; gastrin; angiogenesis ... See more keywords
Association among helicobacter pylori infection, gastrin level and colorectal cancer in patients aged 50 years and over
Sign Up to like & getrecommendations! Published in 2020 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.36.5.1993
Abstract: Objectives: To study the correlations among helicobacter pylori infection, gastrin and colorectal cancer in patients aged over 50 years old. Methods: In this study, the patients diagnosed with colorectal cancer treated in the department of… read more here.
Keywords: gastrin; colorectal cancer; pylori infection; cancer ... See more keywords
Gastroprotective Effect of Azilsartan Through Ameliorating Oxidative Stress, Inflammation, and Restoring Hydroxyproline, and Gastrin Levels in Ethanol-Induced Gastric Ulcer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s365090
Abstract: Objective The present study was designed to evaluate the possible gastroprotective effects of different doses of azilsartan in ethanol-induced gastric ulcers in rats. Methodology Forty-eight male adult Wistar rats were used and allocated randomly into… read more here.
Keywords: gastrin; ethanol induced; hydroxyproline gastrin; induced gastric ... See more keywords