Long‐term symptom control of gastro‐oesophageal reflux disease 12 years after laparoscopic Nissen or 180° anterior partial fundoplication in a randomized clinical trial
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DOI: 10.1002/bjs.10473
Abstract: Laparoscopic 180° anterior fundoplication has been shown to achieve similar reflux control to Nissen fundoplication, with fewer side‐effects, up to 5 years. However, there is a paucity of long‐term follow‐up data on this technique and… read more here.
Keywords: 180 anterior; long term; laparoscopic nissen; oesophageal reflux ... See more keywords
Effects of high‐intensity exercise training on physical fitness, quality of life and treatment outcomes after oesophagectomy for cancer of the gastro‐oesophageal junction: PRESET pilot study
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DOI: 10.1002/bjs5.50337
Abstract: Treatment for cancer of the gastro‐oesophageal junction (GOJ) can result in considerable and persistent impairment of physical fitness and health‐related quality of life (HRQoL). This controlled follow‐up study investigated the feasibility and safety of postoperative… read more here.
Keywords: physical fitness; exercise training; cancer gastro; quality life ... See more keywords
Influence of bouncing and assisted autogenic drainage on acid gastro‐oesophageal reflux in infants
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23677
Abstract: To determine the influence of modern airway clearance techniques using assisted autogenic drainage (AAD), whether or not combined with bouncing, on acid gastro‐oesophageal reflux (GOR) in infants read more here.
Keywords: reflux; acid gastro; group; assisted autogenic ... See more keywords
Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials
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DOI: 10.1007/s12032-017-0898-1
Abstract: Adenocarcinomas of the lower oesophagus and gastro-oesophageal junction are a complex clinico-pathological setting. Multimodality therapy is considered mandatory in most disease presentations. Nevertheless, the most appropriate treatment package has yet to be established. We herein… read more here.
Keywords: lower oesophagus; pre operative; operative treatments; oesophagus gastro ... See more keywords
A systematic review and meta-analysis of PD-1/PD-L1 inhibitors in specific patient subgroups with advanced gastro-oesophageal junction and gastric adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2020.103173
Abstract: BACKGROUND immune checkpoint inhibitors(ICIs) have shown contradictory results in patients with advanced gastro-oesophageal junction/gastric cancer(GOJ/GC). AIM to identify specific patient subgroups that would derive survival benefit from ICIs. METHODS a subgroup meta-analysis of randomised clinical… read more here.
Keywords: patient subgroups; advanced gastro; junction gastric; specific patient ... See more keywords
Gastro-oesophageal reflux disease and hiatus hernia
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DOI: 10.1016/j.mpmed.2019.02.011
Abstract: Abstract Gastro-oesophageal reflux disease (GORD) is a common disorder with an increasing prevalence in th UK. The presence of a hiatus hernia is the strongest risk factor for developing GORD, although not essential. The most… read more here.
Keywords: reflux disease; gastro oesophageal; hiatus hernia; oesophageal reflux ... See more keywords
A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk.
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DOI: 10.1016/j.rmed.2018.06.031
Abstract: Gastro-oesophageal reflux disease (GORD) is a common comorbidity in bronchiectasis, and is often associated with poorer outcomes. The cause and effect relationship between GORD and bronchiectasis has not yet been fully elucidated and a greater… read more here.
Keywords: risk; bronchiectasis; gord; oesophageal reflux ... See more keywords
Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial
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DOI: 10.1016/s0140-6736(18)31257-1
Abstract: BACKGROUND Patients with advanced gastric or gastro-oesophageal junction cancer that progresses on chemotherapy have poor outcomes. We compared pembrolizumab with paclitaxel in patients with advanced gastric or gastro-oesophageal junction cancer that progressed on first-line chemotherapy… read more here.
Keywords: advanced gastric; gastric gastro; pembrolizumab; cancer ... See more keywords
First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial
Sign Up to like & getrecommendations! Published in 2021 at "The Lancet"
DOI: 10.1016/s0140-6736(21)00797-2
Abstract: BACKGROUND First-line chemotherapy for advanced or metastatic human epidermal growth factor receptor 2 (HER2)-negative gastric or gastro-oesophageal junction adenocarcinoma has a median overall survival (OS) of less than 1 year. We aimed to evaluate first-line… read more here.
Keywords: chemotherapy alone; gastro oesophageal; gastric gastro; plus chemotherapy ... See more keywords
Resistance to immune checkpoint inhibitors in advanced gastro-oesophageal cancers.
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DOI: 10.1038/s41416-021-01425-7
Abstract: Immune checkpoint inhibitors (ICIs) have altered the treatment paradigm across a range of tumour types, including gastro-oesophageal cancers. For patients with any cancer type who respond, ICIs can confer long-term disease control and significantly improve… read more here.
Keywords: oesophageal cancers; immune checkpoint; checkpoint inhibitors; cancer ... See more keywords
Gastro‐oesophageal reflux disease in 20 dogs (2012 to 2014)
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DOI: 10.1111/jsap.12646
Abstract: OBJECTIVES To describe the clinical features of canine gastro-oesophageal reflux disease. MATERIALS AND METHODS A search of our medical records produced 20 dogs with clinical signs attributable to oesophageal disease, hyper-regeneratory oesophagopathy and no other… read more here.
Keywords: gastro oesophageal; reflux disease; oesophageal reflux; disease ... See more keywords