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   Articles with "gastro retentive" as a keyword



Fabrication of Aminosilanized Halloysite Based Floating Biopolymer Composites for Sustained Gastro Retentive Release of Curcumin

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recommendations! Published in 2019 at "Macromolecular Research"

DOI: 10.1007/s13233-019-7062-z

Abstract: Being poor solubility and degradation at relatively higher pH present in the small intestine, it is very essential to develop gastro-retentive dosages for the release of curcumin. In this paper, the halloysite nanotubes (HNTs) was… read more here.

Keywords: microscopy; release curcumin; hybrid beads; gastro retentive ... See more keywords
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Fabrication of floating capsule-in- 3D-printed devices as gastro-retentive delivery systems of amoxicillin

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recommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2019.101393

Abstract: Abstract Gastro-retentive drug delivery systems (GRDDS) provide prolonged drug release in the stomach for the treatment of some diseases located in the gastric area, and can improve patient compliance by reducing the required dosing frequency.… read more here.

Keywords: capsule; delivery systems; drug; printed devices ... See more keywords
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Tripolyphosphate‐crosslinked chitosan/poly (ethylene oxide) electrospun nanofibrous mats as a floating gastro‐retentive delivery system for ranitidine hydrochloride

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recommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2018.02.023

Abstract: Graphical abstract Figure. No Caption available. HighlightsChitosan/PEO nanofibrous mats were crosslinked by tripolyphosphate solution.Prepared mat was used as a floating gastro‐retentive delivery system for ranitidine.Structural characteristics of nanofibers were evaluated using different techniques.Swelling profile of… read more here.

Keywords: delivery system; floating gastro; nanofibrous mats; retentive delivery ... See more keywords
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Design and Development of Gastro-retentive Drug Delivery System for Trazodone Hydrochloride: a Promising Alternative to Innovator’s Controlled-Release Tablet

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recommendations! Published in 2022 at "AAPS PharmSciTech"

DOI: 10.1208/s12249-022-02404-8

Abstract: Trazodone hydrochloride (TZN) is a serotonin reuptake inhibitor that treats a major depressive disorder. It exhibits a short plasma half-life of 4.1 h and shows pH-dependent solubility. Above its pKa (6.74), solubility of TZN is… read more here.

Keywords: formulation; trazodone hydrochloride; gastro retentive; tablet ... See more keywords
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Expert design and optimization of ethyl cellulose-poly (ε-caprolactone) blend microparticles for gastro-retentive floating delivery of metformin hydrochloride.

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recommendations! Published in 2021 at "Current drug delivery"

DOI: 10.2174/1567201818666210204164145

Abstract: BACKGROUND Metformin hydrochloride (MH) is an oral anti-hyperglycemic agent belonging to the biguanide class of drugs. OBJECTIVE The present study involves the formulation and evaluation of gastro-retentive floating microparticles containing MH as a model drug… read more here.

Keywords: retentive floating; delivery; drug; metformin hydrochloride ... See more keywords
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Probing the Synergistic Effect of Antibacterial Drug and Oleic Acid in Lipid Based Gastro Retentive Matrices by Melt Molding Method.

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recommendations! Published in 2022 at "Current drug delivery"

DOI: 10.2174/1567201819666220412112104

Abstract: INTRODUCTION Clarithromycin (antibiotic), due to its narrow absorption window in gastrointestinal tract, was taken as a model drug. MATERIALS & METHODS Focusing on the efficient drug delivery system, floating tablets that remain buoyant over gastric… read more here.

Keywords: gastro retentive; drug; spectroscopy; melt molding ... See more keywords
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An Insight on Novel Approaches & Perspectives for Gastro-Retentive Drug Delivery Systems.

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recommendations! Published in 2022 at "Current drug delivery"

DOI: 10.2174/1567201819666220819200236

Abstract: The conventional oral drug delivery systems face a lot of difficulties in the gastrointestinal tract, such as inappropriate drug release and reduction in the efficacy of the doses, which makes this system less susceptible to… read more here.

Keywords: delivery systems; gastro retentive; drug delivery; retentive drug ... See more keywords
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A Complete Sojourn of Current Trends in Gastro-retentive Drug Delivery System: Recent Advances and Patent Survey.

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recommendations! Published in 2023 at "Recent patents on nanotechnology"

DOI: 10.2174/1872210517666230331083346

Abstract: AIMS AND OBJECTIVES The current work aims to provide a complete sojourn on gastro-retentive drug delivery system (GRDDS) along with formulation methods, polymer selection, and in vitro/ in vivo challenges with finished dosage forms Materials… read more here.

Keywords: gastro retentive; complete sojourn; drug delivery; drug ... See more keywords
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FORMULATION AND EVALUATION OF AMOXICILLIN-TRIHYDRATE, METRONIDAZOLE AND FAMOTIDINE LOADED-MUCOADHESIVE GASTRO-RETENTIVE FILMS

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recommendations! Published in 2019 at "International Journal of Applied Pharmaceutics"

DOI: 10.22159/ijap.2019v11i5.33729

Abstract: Objective: To developed mucoadhesive gastro-retentive films of amoxicillin trihydrate, metronidazole and famotidine by using polymers and plasticizer for eradication of H. pylori infection. Methods: The mucoadhesive gastro-retentive films of amoxicillin trihydrate, metronidazole and famotidine were… read more here.

Keywords: mucoadhesive gastro; amoxicillin trihydrate; metronidazole famotidine; retentive films ... See more keywords

Development of Novel Unfolding Film System of Itopride Hydrochloride Using Box-Behnken Design—A Gastro Retentive Approach

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recommendations! Published in 2022 at "Pharmaceuticals"

DOI: 10.3390/ph15080981

Abstract: Currently, gastro-retentive dosage forms achieved a remarkable position among the oral drug delivery systems. This is a broadly used technique to hold the drug delivery systems for a long duration in the gastro intestine (GI)… read more here.

Keywords: system; unfolding film; gastro retentive; drug ... See more keywords
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In Vivo Evaluation of Thiamine Hydrochloride with Gastro-Retentive Drug Delivery in Healthy Human Volunteers Using Gamma Scintigraphy

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recommendations! Published in 2023 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics15020691

Abstract: A floating tablet system containing thiamine hydrochloride, a model drug with a narrow absorption window, was evaluated. The tablet was found to have a floating lag time of less than 30 s with a sustained… read more here.

Keywords: thiamine; state; gastro retentive; tablet ... See more keywords