Epidemiologic Trends of and Factors Associated With Overall Survival for Patients With Gastroenteropancreatic Neuroendocrine Tumors in the United States
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.24750
Abstract: Key Points Question What are the epidemiologic trends of and prognostic factors for gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in patients in the US? Findings In this cohort study of 43 751 patients with GEP-NETs, most cases occurred… read more here.
Keywords: neuroendocrine tumors; associated overall; gastroenteropancreatic neuroendocrine; overall survival ... See more keywords
Follow-up Recommendations for Completely Resected Gastroenteropancreatic Neuroendocrine Tumors
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DOI: 10.1001/jamaoncol.2018.2428
Abstract: There is no consensus on optimal follow-up for completely resected gastroenteropancreatic neuroendocrine tumors. Published guidelines for follow-up are complex and emphasize closer surveillance in the first 3 years after resection. Neuroendocrine tumors have a different… read more here.
Keywords: completely resected; resected gastroenteropancreatic; neuroendocrine tumors; follow recommendations ... See more keywords
Risk factors associated with gastroenteropancreatic neuroendocrine tumors in a cohort of 2.3 million Israeli adolescents
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31589
Abstract: We investigated whether obesity and sociodemographic factors at adolescence are associated with incident gastroenteropancreatic neuroendocrine tumors (GEP‐NET).Our cohort included 2.3 million Israeli adolescents examined at ages 16 to 19 years between 1967 and 2010. The baseline… read more here.
Keywords: small bowel; risk; israeli adolescents; neuroendocrine tumors ... See more keywords
Identification of sequence polymorphisms in the displacement loop region of mitochondrial DNA as a risk factor for gastroenteropancreatic neuroendocrine neoplasm
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22078
Abstract: Gastroenteropancreatic neuroendocrine neoplasms (GEP‐NEN) are relatively rare tumors that arise from the diffuse neuroendocrine system, and the biggest advances in molecular biology have helped in understanding these biological diversity of tumors over the past decades.… read more here.
Keywords: polymorphisms displacement; displacement loop; sequence polymorphisms; identification sequence ... See more keywords
Adjuvant therapy following resection of gastroenteropancreatic neuroendocrine tumors—There is hope, but more data are needed
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DOI: 10.1002/jso.25972
Abstract: We appreciate the thoughtful response provided by Lamberti et al, there is certainly still hope for adjuvant therapy in resected gastroenteropancreatic neuroendocrine tumors (GEP NETs). Given that cytotoxic chemotherapy has been extensively studied in only… read more here.
Keywords: gastroenteropancreatic neuroendocrine; disease; neuroendocrine tumors; therapy ... See more keywords
Supportive therapy in gastroenteropancreatic neuroendocrine tumors: Often forgotten but important
Sign Up to like & getrecommendations! Published in 2018 at "Reviews in Endocrine and Metabolic Disorders"
DOI: 10.1007/s11154-018-9443-6
Abstract: Neuroendocrine tumors (NETs) are a group of rare and heterogeneous malignancies that can develop in various organs. A significant number of gastroenteropancreatic neuroendocrine tumours (GEP-NETs) is functionally active and presents with symptoms related to the… read more here.
Keywords: gastroenteropancreatic neuroendocrine; treatment; supportive therapy; neuroendocrine tumors ... See more keywords
STAT3 Inhibition for Gastroenteropancreatic Neuroendocrine Tumors: Potential for a New Therapeutic Target?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-019-04261-6
Abstract: Background Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are highly vascular neoplasms treated similarly, irrespective of tumor location. The expression of pro-angiogenic factors (STAT3, VEGF, and HIF-1α) and their association with adverse pathologic factors and disease recurrence following… read more here.
Keywords: high stat3; neuroendocrine tumors; expression; gastroenteropancreatic neuroendocrine ... See more keywords
Tumour grade and primary site predict patterns of recurrence and survival in patients with resected gastroenteropancreatic neuroendocrine tumors.
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DOI: 10.1016/j.amjsurg.2021.03.027
Abstract: BACKGROUND Patterns of recurrence help to inform surveillance of patients with resected gastroenteropancreatic neuroendocrine tumors (GEP-NETs). METHODS Patients with GEP-NETs in British Columbia, Canada (2004-2015) were reviewed. Associations between tumor characteristics, recurrence and survival were… read more here.
Keywords: patients resected; recurrence; resected gastroenteropancreatic; patterns recurrence ... See more keywords
Management of Well-differentiated Gastroenteropancreatic Neuroendocrine Tumors (GEPNETs): A Review.
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DOI: 10.1016/j.clinthera.2017.10.010
Abstract: PURPOSE Neuroendocrine tumors (NETs) are heterogeneous tumors that arise from the neuroendocrine cells of the digestive tract and other organs, such as the lung, ovary, and thyroid glands. They can be well differentiated or poorly… read more here.
Keywords: management; well differentiated; neuroendocrine tumors; gastroenteropancreatic neuroendocrine ... See more keywords
The Problem of High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms: Well-Differentiated Neuroendocrine Tumors, Neuroendocrine Carcinomas, and Beyond.
Sign Up to like & getrecommendations! Published in 2018 at "Endocrinology and metabolism clinics of North America"
DOI: 10.1016/j.ecl.2018.05.001
Abstract: High-grade gastroenteropancreatic neuroendocrine neoplasms are well-differentiated neuroendocrine tumors or poorly differentiated small/large cell neuroendocrine carcinoma. Distinguishing these entities relies on different genetic backgrounds and resulting different biology. The new classification creates several problems. Almost all… read more here.
Keywords: neuroendocrine neoplasms; differentiated neuroendocrine; well differentiated; neuroendocrine tumors ... See more keywords
Treatment Patterns and Clinical Outcomes in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors Treated in the Community Practice Setting in the United States
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DOI: 10.1097/mpa.0000000000000955
Abstract: Objective This study was conducted to understand treatment patterns and clinical outcomes in metastatic gastroenteropancreatic neuroendocrine tumor patients treated in a large community oncology network. Methods This retrospective study used the McKesson Specialty Health/US Oncology… read more here.
Keywords: patterns clinical; treatment; gastroenteropancreatic neuroendocrine; oncology ... See more keywords