Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.6b00888
Abstract: Improved models of the gastrointestinal environment have great potential to assist the complex process of drug formulation. Molecular dynamics (MD) is a powerful method for investigating phase behavior at a molecular level. In this study… read more here.
Keywords: phase; computational models; models gastrointestinal; phase behavior ... See more keywords
Two-component systems regulate bacterial virulence in response to the host gastrointestinal environment and metabolic cues
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2127196
Abstract: ABSTRACT Two-component systems are ubiquitous signaling mechanisms in bacteria that enable intracellular changes from extracellular cues. These bacterial regulatory systems couple external stimuli to control genetic expression via an autophosphorylation cascade that transduces membrane signals… read more here.
Keywords: component systems; gastrointestinal environment; virulence; two component ... See more keywords