Evolution and recurrence of gastrointestinal immune-related adverse events induced by immune checkpoint inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of cancer"
DOI: 10.1016/j.ejca.2018.10.006
Abstract: BACKGROUND Immune checkpoint inhibitors (ICIs), such as anti-CTLA-4 and anti-PD-1 antibodies, are effective against several malignancies. They are associated with gastrointestinal immune-related adverse events (GI-IrAEs), which may be severe and lead to ICI discontinuation. We… read more here.
Keywords: immune checkpoint; gastrointestinal immune; checkpoint inhibitors; recurrence ... See more keywords
Exploiting the Lymph Nodes-Amplifying Effect for Potent Systemic and Gastrointestinal Immune Responses via Polymer/Lipid Nanoparticles.
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.9b04071
Abstract: Parenteral vaccinations are not able to elicit effective systemic and gastrointestinal immune protection simultaneously since the lymphocytes are typically restricted to primed tissues. Although all-trans retinoic acid (atRA) was reported to trigger the gut-homing of… read more here.
Keywords: immune; systemic gastrointestinal; gastrointestinal immune; immune responses ... See more keywords