Implications of superporous hydrogel composites-based gastroretentive drug delivery systems with improved biopharmaceutical performance of fluvastatin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101668
Abstract: Abstract The present research work describes the systematic development and characterization of novel gastroretentive drug delivery system containing superporous hydrogel composites for improving the bioavailability and antihyperlipidemic activity. The superporous hydrogels of fluvastatin exhibited swelling… read more here.
Keywords: drug; drug delivery; gastroretentive drug; superporous hydrogel ... See more keywords
Development and Characterization of PCL Electrospun Membrane-Coated Bletilla striata Polysaccharide-Based Gastroretentive Drug Delivery System
Sign Up to like & getrecommendations! Published in 2020 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-019-1607-5
Abstract: The purpose of this study was to investigate the potential of Bletilla striata polysaccharide (BSP, a natural glucomannan material) for the development of a gastroretentive drug delivery system for the first time. Novel BSP-based porous… read more here.
Keywords: gastroretentive drug; drug delivery; delivery; drug ... See more keywords
Construction of catechol-grafted chitosan alginate/barium sulfate microcapsules for computed tomography real-time imaging and gastroretentive drug delivery
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s204237
Abstract: Background: The gastroretentive drug delivery system is an effective administration route, which can improve the bioavailability of the drug and the therapeutic effect by prolonging the release time of the drug and controlling the release… read more here.
Keywords: cat mcs; drug; drug delivery; gastroretentive drug ... See more keywords
Gastroretentive Drug Delivery System in Cancer Chemotherapy.
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DOI: 10.2174/1567201819666220608141124
Abstract: BACKGROUND Chemotherapy for stomach cancer often includes several side effects. The primary reasons for the failure of such treatment approaches are low drug concentrations in target tissues and a short stomach residence time. OBJECTIVE Gastroretentive… read more here.
Keywords: gastroretentive drug; drug delivery; chemotherapy; drug ... See more keywords
Mechanically Robust Gastroretentive Drug-Delivery Systems Capable of Controlling Dissolution Behaviors of Coground β-Lapachone
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DOI: 10.3390/pharmaceutics11060271
Abstract: In this study, we aimed to design a highly swellable and mechanically robust matrix tablet (SMT) as a gastroretentive drug-delivery system (GRDDS) capable of improving the dissolution behavior of β-lapachone with low aqueous solubility. For… read more here.
Keywords: gastroretentive drug; lapachone; mechanically robust; dissolution ... See more keywords
Overview on Trends in Development of Gastroretentive Drug Delivery System
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DOI: 10.5958/0974-360x.2019.00975.2
Abstract: The present review on gastroretentive Drug Delivery Systems was aim with overview on various trends in development of gastroretentive approaches in the area of site-specific orally administered controlled release drug delivery. Gastroretentive dosage form can… read more here.
Keywords: trends development; system; drug; drug delivery ... See more keywords