Gellan gum based gastroretentive tablets for bioavailability enhancement of cilnidipine in human volunteers.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.01.199
Abstract: Cilnidipine, a fourth-generation both L-and N-type calcium channel blocker (CCB) is safe and effective in lowering blood-pressure without reflex tachycardia compared to other dihydropyridine CCBs. However, its low solubility coupled with extensive first-pass metabolism results… read more here.
Keywords: bioavailability; drug release; gellan gum; cilnidipine ... See more keywords