The lignin-degrading abilities of Gelatoporia subvermispora gat1 and pex1 mutants generated via CRISPR/Cas9.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental microbiology"
DOI: 10.1111/1462-2920.16372
Abstract: White-rot fungi efficiently degrade wood lignin; however, the mechanisms involved remain largely unknown. Recently, a forward genetics approach to identify several genes in Pleurotus ostreatus (Agaricales) in which mutations cause defects in wood lignin degradation… read more here.
Keywords: crispr cas9; lignin; gat1; pex1 ... See more keywords
A comparative review on the well-studied GAT1 and the understudied BGT-1 in the brain
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1145973
Abstract: γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system (CNS). Its homeostasis is maintained by neuronal and glial GABA transporters (GATs). The four GATs identified in humans are GAT1 (SLC6A1), GAT2… read more here.
Keywords: well studied; gat1; transporter; review well ... See more keywords
GRID-independent molecular descriptor analysis and molecular docking studies to mimic the binding hypothesis of γ-aminobutyric acid transporter 1 (GAT1) inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "PeerJ"
DOI: 10.7717/peerj.6283
Abstract: Background The γ-aminobutyric acid (GABA) transporter GAT1 is involved in GABA transport across the biological membrane in and out of the synaptic cleft. The efficiency of this Na+ coupled GABA transport is regulated by an… read more here.
Keywords: grid independent; transporter gat1; gat1; acid ... See more keywords