The Hypomorphic Gata1low Mutation Induces Fibrosis in Multiple Organs
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DOI: 10.1182/blood-2018-99-110927
Abstract: Mice carrying the hypomorphic mutation which reduces the transcription factor GATA1 in megakaryocytes (Gata1low mice), develop by 8-months myelofibrosis a phenotype resembling primary myelofibrosis, the most severe of myeloproliferative neoplasms (Vannucchi et al Blood 2002;100:1123).… read more here.
Keywords: gata1low mice; fibrosis; fibrosis multiple; mice ... See more keywords