3098 – THE ROLE OF GATA2 IN HSC GENERATION THROUGH ENDOTHELIAL-TO-HEMATOPOIETIC TRANSITION
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DOI: 10.1016/j.exphem.2020.09.111
Abstract: GATA2 is the most frequently mutated gene in childhood AML. These patients have germline mutations in one allele of GATA2 and have a high predisposition for MDS/AML. Also, in mouse, Gata2 is required for embryonic… read more here.
Keywords: endothelial hematopoietic; gata2 haploinsufficiency; hsc generation; gata2 ... See more keywords