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Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.973
Abstract: Abstract Background Patients with myeloid malignancies are at risk of invasive aspergillosis (IA), a cause of significant morbidity and mortality. Identification of patients at higher risk for IA may help optimize prophylactic or preemptive treatment…
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Keywords:
gata2 mutations;
risk;
among patients;
invasive aspergillosis ... See more keywords
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Published in 2021 at "Blood advances"
DOI: 10.1182/bloodadvances.2020002854
Abstract: Invasive fungal disease (IFD) can be a severe treatment complication in patients with myeloid malignancies, but current risk models do not incorporate disease-specific factors, such as somatic gene mutations. Germline GATA2 deficiency is associated with…
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Keywords:
gata2 mutations;
risk;
disease;
somatic gata2 ... See more keywords
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Published in 2020 at "Blood advances"
DOI: 10.1182/bloodadvances.2020002953
Abstract: The surge of human genetic information, enabled by increasingly facile and economically feasible genomic technologies, has accelerated discoveries on the relationship of germline genetic variation to hematologic diseases. For example, germline variation in GATA2, encoding…
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Keywords:
gata2 mutations;
mutations hematologic;
disease many;
gata2 ... See more keywords