Long noncoding RNA MEG3 inhibits oral squamous cell carcinoma progression via GATA3
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13532
Abstract: Oral squamous cell carcinoma (OSCC) accounts for about 90% of oral cancers. Expression of the long noncoding RNA (lncRNA) maternally expressed 3 (MEG3) has previously been reported to be downregulated in OSCC, and its overexpression… read more here.
Keywords: cell carcinoma; squamous cell; long noncoding; gata3 ... See more keywords
GATA3 differential expression in neuroblastoma and nephroblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cytopathology"
DOI: 10.1002/cncy.21952
Abstract: We have read with great interest the report by Wiles et al, published in Cancer Cytopathology, about the immunohistochemical expression of the GATA3 antibody in cytological material from neuroblastomas. They evaluated GATA3 immunohistochemical expression in… read more here.
Keywords: expression neuroblastoma; gata3; positivity; expression ... See more keywords
A pilot study: Comparison of TRPS1 and GATA3 immunoperoxidase staining using cytologic smears in entities reportedly positive for GATA3
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22623
Abstract: Metastatic breast carcinoma (mBC) is frequently encountered and may be challenging to diagnose as the tumor cells can morphologically resemble carcinomas of other primary origins. An additional challenge is that direct smears are often the… read more here.
Keywords: comparison trps1; gata3; trps1 gata3; trps1 ... See more keywords
GATA3 germline variant is associated with CRLF2 expression and predicts outcome in pediatric B‐cell precursor acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.1002/gcc.22748
Abstract: The germline variant at rs3824662 in GATA3 is a risk locus for Philadelphia‐like acute lymphoblastic leukemia (Ph‐like ALL), the biological subtype of B‐cell precursor (BCP)‐ALL defined by a distinct gene expression profile and the presence… read more here.
Keywords: germline variant; expression; crlf2 expression; gata3 ... See more keywords
LANA regulates miR‐155/GATA3 signaling axis by enhancing c‐Jun/c‐Fos interaction to promote the proliferation and migration of KSHV‐infected cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28255
Abstract: Kaposi's sarcoma (KS) is the second most common tumor in people infected with human immunodeficiency virus worldwide, but its pathogenesis is still unclear. In this study, we discovered that the expression of GATA‐binding protein 3… read more here.
Keywords: mir 155; kshv infected; jun fos; infected cells ... See more keywords
Genomic and proteomic profiling of GATA3 mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes
Sign Up to like & getrecommendations! Published in 2025 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-025-07710-w
Abstract: GATA3 mutations are among the most common alterations in hormone receptor-positive (HR+) breast cancer (BC), yet these have no targeted therapies. MDM2 is an E3 ubiquitin ligase that targets p53 for degradation, and pre-clinical data… read more here.
Keywords: breast cancer; breast; hormone receptor; analysis ... See more keywords
Strong androgen receptor expression can aid in distinguishing GATA3+ metastases.
Sign Up to like & getrecommendations! Published in 2018 at "Human pathology"
DOI: 10.1016/j.humpath.2018.01.024
Abstract: GATA3 is a transcription factor used clinically as a marker of breast or urothelial differentiation. A marker is yet needed to distinguish this in the case of the GATA3-positive tumor of unknown origin. We tested… read more here.
Keywords: breast; gata3; origin; expression ... See more keywords
The potential utility of GATA3 for diagnosis of malignant pleural mesotheliomas.
Sign Up to like & getrecommendations! Published in 2020 at "Human pathology"
DOI: 10.1016/j.humpath.2020.08.005
Abstract: Malignant pleural mesothelioma is associated with asbestos exposure and poor outcomes. The usefulness of immunohistochemistry for diagnosis of sarcomatoid mesothelioma, especially the desmoplastic type, is limited and more effective markers are required. GATA3 has been… read more here.
Keywords: sarcomatoid mesothelioma; gata3; diagnosis; mesotheliomas ... See more keywords
GATA3 Encapsulated by Tumor-Associated Macrophage-Derived Extracellular Vesicles Promotes Immune Escape and Chemotherapy Resistance of Ovarian Cancer Cells by Upregulating the CD24/Siglec-10 Axis.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00557
Abstract: Tumor-associated macrophages (TAMs) possess great potential in the development of ovarian cancer (OC). Aberrant GATA-binding protein-3 (GATA3) expression has been found in TAM-derived extracellular vesicles (EVs). This study is intended to investigate the regulatory mechanism… read more here.
Keywords: cd24 siglec; gata3; immune escape; resistance ... See more keywords
A GATA3 Targeting Nucleic Acid Nanocapsule for In Vivo Gene Regulation in Asthma.
Sign Up to like & getrecommendations! Published in 2021 at "ACS nano"
DOI: 10.1021/acsnano.0c07781
Abstract: Allergic asthma is one of the leading chronic lung diseases of both children and adults worldwide, resulting in significant morbidity and mortality in affected individuals. Many patients have severe asthma, which is refractory to treatment,… read more here.
Keywords: peptide cross; gata3; cross linked; nucleic acid ... See more keywords
A neonatal case of HDR syndrome and a vascular ring with a novel GATA3 mutation.
Sign Up to like & getrecommendations! Published in 2019 at "Human genome variation"
DOI: 10.1038/s41439-019-0087-1
Abstract: HDR syndrome (OMIM #146255) is caused by haploinsufficiency of the GATA3 gene. A vascular ring has not been reported in patients with GATA3-associated HDR syndrome. We report a neonatal case of HDR syndrome and a… read more here.
Keywords: hdr syndrome; gata3; neonatal case; case hdr ... See more keywords