Assembly of Dynamic Gated and Cascaded Transient DNAzyme Networks
Sign Up to like & getrecommendations! Published in 2022 at "ACS Nano"
DOI: 10.1021/acsnano.1c11631
Abstract: The dynamic transient formation and depletion of G-quadruplexes regulate gene replication and transcription. This process was found to be related to various diseases such as cancer and premature aging. We report on the engineering of… read more here.
Keywords: dynamic gated; gated cascaded; dnazyme; assembly dynamic ... See more keywords
Autoinhibited transient, gated, and cascaded dynamic transcription of RNAs
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abq5947
Abstract: Following transient spatiotemporal misregulation of gene expression programs by native transcription machineries, we introduce a versatile biomimetic concept to design transient dynamic transcription machineries, revealing gated and cascaded temporal transcription of RNAs. The concept is… read more here.
Keywords: gated cascaded; dynamic transcription; transcription; transient gated ... See more keywords