Loss of voltage-gated hydrogen channel 1 expression reveals heterogeneous metabolic adaptation to intracellular acidification by T cells
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DOI: 10.1172/jci.insight.147814
Abstract: Voltage-gated hydrogen channel 1 (Hvcn1) is a voltage-gated proton channel, which reduces cytosol acidification and facilitates the production of ROS. The increased expression of this channel in some cancers has led to proposing Hvcn1 antagonists… read more here.
Keywords: gated hydrogen; intracellular acidification; voltage gated; acidification ... See more keywords