Topologically switchable and gated transcription machinery
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DOI: 10.1039/d2sc01599d
Abstract: Topological barriers control in nature the transcription machinery, thereby perturbing gene expression. Here we introduce synthetically designed DNA templates that include built-in topological barriers for switchable, triggered-controlled transcription of RNA aptamers. This is exemplified with… read more here.
Keywords: transcription; rna; rna aptamer; gated transcription ... See more keywords