Drug Development in Channelopathies: Allosteric Modulation of Ligand-Gated and Voltage-Gated Ion Channels.
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DOI: 10.1021/acs.jmedchem.0c01304
Abstract: Ion channels have been characterized as promising drug targets for treatment of numerous human diseases. Functions of ion channels can be fine-tuned by allosteric modulators, which interact with channels and modulate their activities by binding… read more here.
Keywords: gated voltage; ion channels; gated ion; ion ... See more keywords