A gating lever and molecular logic gate that couple voltage and calcium sensor activation to opening in BK potassium channels
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DOI: 10.1126/sciadv.abq5772
Abstract: BK channels uniquely integrate voltage and calcium signaling in diverse cell types through allosteric activation of their K+-conducting pore by structurally distinct V and Ca2+ sensor domains. Here, we define mechanisms and interaction pathways that… read more here.
Keywords: gating lever; voltage; sensor activation; voltage calcium ... See more keywords