Structural Basis for Gating Pore Current in Periodic Paralysis
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DOI: 10.1038/s41586-018-0120-4
Abstract: Potassium-sensitive hypokalaemic and normokalaemic periodic paralysis are inherited skeletal muscle diseases characterized by episodes of flaccid muscle weakness1,2. They are caused by single mutations in positively charged residues (‘gating charges’) in the S4 transmembrane segment… read more here.
Keywords: periodic paralysis; paralysis; voltage sensor; gating pore ... See more keywords