Who seeks finds. Gaucher’s disease: a rare case of thrombocytopenia
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Hematology"
DOI: 10.1007/s12185-020-02824-x
Abstract: In July 2019, a 68-year-old man was admitted to our institution for isolated thrombocytopenia (platelet count, 73 × 109/L) without anemia or abnormalities in white blood cells. The patient also referred bone pain. Standard exams… read more here.
Keywords: disease rare; gaucher disease; gaucher cells; seeks finds ... See more keywords
Gaucher disease: An orphan disease with significant osseous manifestations
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular and Molecular Medicine"
DOI: 10.15761/jcmm.1000110
Abstract: Gaucher disease, the most common of the lysosomal storage diseases, is a systematic familial disease classified in “orphan diseases’’, a group of rare disorders with prevalence of 1:50,000 or lower in the general population. Gaucher… read more here.
Keywords: gaucher disease; disease orphan; gaucher cells; disease ... See more keywords
Images from the Haematologica Atlas of Hematologic Cytology: Gaucher disease
Sign Up to like & getrecommendations! Published in 2022 at "Haematologica"
DOI: 10.3324/haematol.2022.281777
Abstract: Gaucher disease is an inherited lysosomal storage disease characterized by the accumulation of glucocerebrosides (glu-cosylceramide), in macrophages of liver, spleen, and bone marrow. This metabolic disorder results from a defect in the lysosomal β -glucocerebrosidase… read more here.
Keywords: gaucher cells; gaucher; bone marrow; cytology ... See more keywords
Phagocytosis of Erythrocytes from Gaucher Patients Induces Phenotypic Modifications in Macrophages, Driving Them toward Gaucher Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147640
Abstract: Gaucher disease (GD) is caused by glucocerebrosidase deficiency leading to the accumulation of sphingolipids in macrophages named “Gaucher’s Cells”. These cells are characterized by deregulated expression of cell surface markers, abnormal secretion of inflammatory cytokines,… read more here.
Keywords: gaucher patients; gaucher cells; gaucher; phagocytosis erythrocytes ... See more keywords