Gaussian network model can be enhanced by combining solvent accessibility in proteins
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-07677-9
Abstract: Gaussian network model (GNM), regarded as the simplest and most representative coarse-grained model, has been widely adopted to analyze and reveal protein dynamics and functions. Designing a variation of the classical GNM, by defining a… read more here.
Keywords: solvent accessibility; gnm; parameter free; model ... See more keywords
Extending the Gaussian network model: integrating local, allosteric, and structural factors for improved residue-residue correlation analysis
Sign Up to like & getrecommendations! Published in 2025 at "Physical Biology"
DOI: 10.1088/1478-3975/ae1dc1
Abstract: The Gaussian network model (GNM) has been successful in explaining protein dynamics by modeling proteins as elastic networks of alpha carbons connected by harmonic springs. However, its uniform interaction assumption and neglect of higher-order correlations… read more here.
Keywords: information; correlation; network model; model ... See more keywords
Estimation of a genetic Gaussian network using GWAS summary data.
Sign Up to like & getrecommendations! Published in 2024 at "Biometrics"
DOI: 10.1093/biomtc/ujae148
Abstract: A genetic Gaussian network of multiple phenotypes, constructed through the inverse matrix of the genetic correlation matrix, is informative for understanding the biological dependencies of the phenotypes. However, its estimation may be challenging because the… read more here.
Keywords: genetic gaussian; gwas summary; estimation genetic; estimation ... See more keywords
Topology Optimization of the IPMSM for HEVs Using a Normalized Gaussian Network With Divided Region Method for Weighting Coefficients
Sign Up to like & getrecommendations! Published in 2024 at "IEEE Access"
DOI: 10.1109/access.2024.3498333
Abstract: In this paper, topology optimization of the rotor flux-barrier of an interior permanent magnet synchronous motor using a normalized Gaussian network is proposed to improve traction in a hybrid electric vehicle. The flux-barrier that impacts… read more here.
Keywords: topology optimization; weighting coefficients; topology; normalized gaussian ... See more keywords
Unsupervised Tissue Segmentation via Deep Constrained Gaussian Network
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Medical Imaging"
DOI: 10.1109/tmi.2022.3195123
Abstract: Tissue segmentation is the mainstay of pathological examination, whereas the manual delineation is unduly burdensome. To assist this time-consuming and subjective manual step, researchers have devised methods to automatically segment structures in pathological images. Recently,… read more here.
Keywords: tissue segmentation; segmentation; gaussian network; constrained gaussian ... See more keywords
PSP-GNM: Predicting Protein Stability Changes upon Point Mutations with a Gaussian Network Model
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810711
Abstract: Understanding the effects of missense mutations on protein stability is a widely acknowledged significant biological problem. Genomic missense mutations may alter one or more amino acids, leading to increased or decreased stability of the encoded… read more here.
Keywords: protein stability; gaussian network; gnm; psp gnm ... See more keywords