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Published in 2022 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2022.121630
Abstract: Oral gavage is the most common way to administer drug formulations orally to rats. Yet, the technique applied and its influence on gastrointestinal (GI) transit receive little attention. This study aims to investigate the impact…
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Keywords:
drug;
gavage;
gastrointestinal transit;
oral gavage ... See more keywords
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Published in 2020 at "Nutritional Neuroscience"
DOI: 10.1080/1028415x.2020.1733813
Abstract: ABSTRACT Objectives: Oral gavage and time-restricted feeding are common delivery methods for dietary supplementation to rodents. However, the stress associated with selected feeding regimens could represent a confounding variable. In rodents, the adolescence period is…
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Keywords:
oral gavage;
restricted feeding;
anxiety;
supplementation ... See more keywords
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Published in 2022 at "Journal of Animal Science"
DOI: 10.1093/jas/skac361
Abstract: Abstract Excess dietary amino acids (AA) may negatively affect feed intake in pigs. Previous results showed that Lys, Leu, Ile, Phe, and Glu significantly increased gut peptide secretion (i.e., cholecystokinin, glucagon-like peptide 1). However, the…
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Keywords:
leu ile;
feed intake;
gavage;
duration ... See more keywords
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Published in 2018 at "Laboratory Animals"
DOI: 10.1177/0023677218756156
Abstract: Oral gavage is commonly used in pre-clinical drug evaluation, but is potentially aversive and may induce behavioral effects independent of compounds under investigation. This study examined the combined effects of repeated oral gavage and disease…
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Keywords:
oral gavage;
anxiety like;
gavage;
mice ... See more keywords
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Published in 2021 at "Toxicologic Pathology"
DOI: 10.1177/01926233211004873
Abstract: The tolerability of single daily gavage doses of 0.5% or 2.0% (wt/vol) sodium lauryl sulfate (SLS) in 11- to 12-week-old male CD-1 mice was evaluated in a study of 3 months in duration. Live-phase, gross…
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Keywords:
lauryl sulfate;
male mice;
sodium lauryl;
gavage ... See more keywords
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Published in 2019 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370219838203
Abstract: Although there are numerous Institutional Animal Care and Use Committee (IACUC) protocols aimed at standardizing the oral administration (gavage) of liquid chemicals to laboratory rodents, there is ample variability across protocols, and there are no…
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Keywords:
communities mice;
consensus;
gavage;
oral administration ... See more keywords
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Published in 2017 at "Microbiome"
DOI: 10.1186/s40168-017-0306-2
Abstract: BackgroundHuman microbiota-associated (HMA) animal models relying on germ-free recipient mice are being used to study the relationship between intestinal microbiota and human disease. However, transfer of microbiota into germ-free animals also triggers global developmental changes…
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Keywords:
microbiota;
antibiotic conditioning;
gavage;
germ free ... See more keywords
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Published in 2021 at "Experimental Animals"
DOI: 10.1538/expanim.20-0200
Abstract: It is known that administering a gavage to rodents evokes a cardiac reflex, due to gastrointestinal stimulation. Consequently, it is difficult to evaluate changes in hemodynamics after a single oral dose of a pungent or…
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Keywords:
gastric tube;
condition;
gavage;
hemodynamic alterations ... See more keywords
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1
Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.907986
Abstract: Background and Aim Research has shown that green tea catechins may influence the activity of drug metabolizing enzymes and drug transporters. We examined whether epigallocatechin-3-gallate (EGCG) affected the pharmacokinetics and pharmacodynamics of bisoprolol in rats.…
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Keywords:
egcg;
pharmacokinetics pharmacodynamics;
gavage;
egcg bisoprolol ... See more keywords
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Published in 2020 at "Asian Pacific Journal of Reproduction"
DOI: 10.4103/2305-0500.281076
Abstract: Objective: To assess the effect of short-term gavage of ethanolic extract of Imperata cylindrica L root on the ovarian activity and estrus behavior of female mice. Methods: Eighteen virgin female ddY mice, 8 to 10…
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Keywords:
imperata cylindrica;
cylindrica root;
group;
ethanolic extract ... See more keywords