Knockdown of IGF2BP3 inhibits the tumorigenesis of gallbladder cancer and modifies tumor microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Drug Development Research"
DOI: 10.1002/ddr.22000
Abstract: Gallbladder cancer (GBC) ranks seventh among the gastrointestinal cancers. Messenger RNAs (mRNAs) could regulate the progression of GBC. For the purpose of exploring the targets for GBC treatment, RNA sequencing was used to identify the… read more here.
Keywords: cell; knockdown igf2bp3; gbc; gbc cells ... See more keywords
Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway
Sign Up to like & getrecommendations! Published in 2017 at "Cytotechnology"
DOI: 10.1007/s10616-017-0153-9
Abstract: Oxymatrine extracted from Sophora flavescens Ait as a natural polyphenolic phytochemical has been demonstrated to exhibit anti-tumor effects on various cancers, including Gallbladder carcinoma (GBC). However, its underlying mechanisms of function are largely unknown in… read more here.
Keywords: gbc cells; akt; pi3k akt; gallbladder carcinoma ... See more keywords
The microRNA cluster miR-214/miR-3120 prevents tumor cell switching from an epithelial to a mesenchymal-like phenotype and inhibits autophagy in gallbladder cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2020.109887
Abstract: Tumor cells switch from an epithelial to a mesenchymal-like phenotype, which represents a key hallmark of human cancer metastasis, including gallbladder cancer (GBC). A large set of microRNAs (miRNAs/miRs) have been studied to elucidate their… read more here.
Keywords: gbc cells; 214 3120; epithelial mesenchymal; gbc ... See more keywords
Effects of lncRNA MEG3 on proliferation and apoptosis of gallbladder cancer cells through regulating NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202006_21649
Abstract: OBJECTIVE To explore the effects of long non-coding ribonucleic acid (lncRNA) maternally expressed gene 3 (MEG3) on proliferation and apoptosis of gallbladder cancer (GBC) cells and its molecular mechanism. MATERIALS AND METHODS The relative expression… read more here.
Keywords: gbc cells; proliferation apoptosis; lncrna meg3; proliferation ... See more keywords
MicroRNA-195-5p inhibits malignant progression of gallbladder cancer by regulating Wnt3a.
Sign Up to like & getrecommendations! Published in 2021 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202112_27610
Abstract: OBJECTIVE We aimed at investigating whether microRNA-195-5p inhibits the malignant proliferation of gallbladder cancer (GBC) via regulating Wnt3a; meanwhile, its relationship with the clinicopathological parameters and prognosis of patients with GBC was also explored. PATIENTS… read more here.
Keywords: group; gbc cells; proliferation; gbc ... See more keywords