A three‐microRNA signature identifies two subtypes of glioblastoma patients with different clinical outcomes
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12047
Abstract: Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumor in adults, characterized by aggressive growth, limited response to therapy, and inexorable recurrence. Because of the extremely unfavorable prognosis of GBM, it is… read more here.
Keywords: microrna signature; identifies two; gbm; signature identifies ... See more keywords
The sex‐dependent role of the androgen receptor in glioblastoma: results of molecular analyses
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13262
Abstract: We sought to analyse the androgen receptor (AR) in glioblastoma (GBM) due to the location of the AR gene on chromosome X, often reported with shorter survival and higher prevalence of GBM among males. Copy… read more here.
Keywords: sex dependent; androgen receptor; expression; receptor glioblastoma ... See more keywords
Glioblastoma in natalizumab‐treated multiple sclerosis patients
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.428
Abstract: We present two natalizumab‐treated multiple sclerosis patients who developed glioblastoma multiforme (GBM) with variable outcomes. One patient had an isocitrate dehydrogenase (IDH)‐wildtype GBM with aggressive behavior, who declined treatment and died 13 weeks after symptoms… read more here.
Keywords: natalizumab treated; gbm; multiple sclerosis; sclerosis patients ... See more keywords
Organic Small Molecule Contrast Agent for Targeted Photoacoustic Imaging of Patient‐Derived Brain Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201640
Abstract: Traditional glioblastoma (GBM) cell lines do not maintain the heterogeneity of the original tumor, cell interactions, and therapy response, thus limiting their investigation in GBM theranostics. Herein, a kind of GBM tumor‐targeting nanoparticles (NPs) TCFNP@iRGD… read more here.
Keywords: contrast agent; patient derived; gbm;
Dynamically Crosslinked Poly(ethylene‐glycol) Hydrogels Reveal a Critical Role of Viscoelasticity in Modulating Glioblastoma Fates and Drug Responses in 3D
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202147
Abstract: Glioblastoma multiforme (GBM) is the most prevalent and aggressive brain tumor in adults. Hydrogels have been employed as 3D in vitro culture models to elucidate how matrix cues such as stiffness and degradation drive GBM… read more here.
Keywords: viscoelasticity; drug responses; gbm; drug ... See more keywords
Synchronous Disintegration of Ferroptosis Defense Axis via Engineered Exosome‐Conjugated Magnetic Nanoparticles for Glioblastoma Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105451
Abstract: Glioblastoma (GBM) is one of the most fatal central nervous system tumors and lacks effective or sufficient therapies. Ferroptosis is a newly discovered method of programmed cell death and opens a new direction for GBM… read more here.
Keywords: defense axis; magnetic nanoparticles; gbm; disintegration ... See more keywords
Virome assembly and annotation in brain tissue based on next‐generation sequencing
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3325
Abstract: The glioblastoma multiforme (GBM) is one of the deadliest tumors. It has been speculated that virus plays a role in GBM but the evidences are controversy. Published researches are mainly limited to studies on the… read more here.
Keywords: annotation; gbm; brain; virome assembly ... See more keywords
miR‐802 inhibits the proliferation, invasion, and epithelial‐mesenchymal transition of glioblastoma multiforme cells by directly targeting SIX4
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3451
Abstract: It is well known that the sine oculis homeobox 4 (SIX4) expression is very relevant to the progression of multiple cancers. Moreover, we found that miR‐802 could directly target the SIX4. However, the precise mechanism… read more here.
Keywords: gbm; mir 802; proliferation invasion; six4 ... See more keywords
Estrogen receptor variant ER‐α36 facilitates estrogen signaling via EGFR in glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11877
Abstract: Glioblastoma (GBM) is a deadly and common primary brain tumor. Poor prognosis is linked to high proliferation and cell heterogeneity. Sex differences may play a role in patient outcome. Previous studies showed that ER‐α36, a… read more here.
Keywords: signaling via; estrogen receptor; estrogen; gbm ... See more keywords
miR96- and miR182-driven regulation of cytoskeleton results in inhibition of glioblastoma motility.
Sign Up to like & getrecommendations! Published in 2023 at "Cytoskeleton"
DOI: 10.1002/cm.21754
Abstract: Glioblastoma multiforme (GBM) is one of the most common forms of brain tumors. As an excessively invasive tumor type, GBM cannot be fully cured due to its invasion ability into the healthy brain tissues. Therefore,… read more here.
Keywords: gbm; motility; spastin palladin; mir96 mir182 ... See more keywords
Proteome profiling of salivary small extracellular vesicles in glioblastoma patients.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer"
DOI: 10.1002/cncr.34888
Abstract: BACKGROUND Extracellular vesicles (EVs) play a critical role in intercellular communication under physiological and pathological conditions, including cancer. EVs cargo reflects their cell of origin, suggesting their utility as biomarkers. EVs are detected in several… read more here.
Keywords: salivary small; extracellular vesicles; saliva samples; evs ... See more keywords